Results 141 to 150 of about 1,601,243 (284)

The Current Status of the 3Rs Principles in Animal Use in Bosnia and Herzegovina: Overview and Future Perspectives. [PDF]

Animals (Basel)
Smajlhodžić-Deljo M, Pehlivanović Kelle B, Elezović A, Bejdić P, Dervišević A, Kitsara M, Neuhaus W.   +6 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The EU Midwifery Directive and Professional Strengthening in New EU Member States and Candidate Countries. [PDF]

Healthcare (Basel)
Brigante L, Drandić D, Vera V, Mivšek AP, Stanek Zidarič T, Kurbanović M, Veselá L, Wilhelmová R, Nagórska M, Lyutakova D, Liepinaitienė A, Kryeziu B, Hakimi S, Đido V, Cheprasova L, Honcharenko O.   +15 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Pesticide active substances that do not require a review of the existing maximum residue levels under Article 12 of Regulation (EC) No 396/2005. [PDF]

EFSA J
European Food Safety Authority (EFSA).
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Nursing Education Pathways in Europe and the Politics of Educational Standards: A Call to Action. [PDF]

J Nurs Scholarsh
Sousa JP, Bianchi M, Gašpert T, Luiking ML, Collins DA, Grinberg K, Červený M, Shao CH, Warshawski S, Freitas O, Alves M, Baron S, Nagórska M, Frazer K.   +13 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Development of Legal and Practical Framework for Naturally Occurring Radioactive Materials (NORM) Management. [PDF]

Environ Manage
Michalik B, Bzowski Z, Makuła H, Rovenská KN, Ženatá I, Law G.   +5 more
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source