Results 161 to 170 of about 396,234 (309)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Occupational exposure to cadmium: protocol for a scoping review. [PDF]
BMJ OpenPaulo MS +8 more
europepmc +1 more source
Cross compliance and competitiveness of the European beef and pig sector [PDF]
Beef and pig production are important sectors affected by the cross-compliance policy. Full compliance with SMRs and GAECs generates costs and benefits which may have an impact on the competitiveness of these sectors on the world market.
Dillen, K. +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Multi-Residue Determination and Risk Assessment of EU-Relevant Pharmaceuticals, Pesticides, and UV-Filters in Drinking Water. [PDF]
Pharmaceuticals (Basel)Quintela IM +4 more
europepmc +1 more source
The EU Emissions Trading Directive: Opportunities and Potential Pitfalls [PDF]
The European Union is on the verge of establishing an emissions trading program ten times the size of the Acid Rain trading program in the United States.
Kruger, Joseph, Pizer, William
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Crossing silos: how changes in EU chemicals policy and legislation are reflected in its pharmaceutical policy and legislation. [PDF]
J Pharm Policy PractMiettinen M.
europepmc +1 more source
Allocation of Carbon Emission Certificates in the Power Sector: How generators profit from grandfathered rights [PDF]
To meet its Kyoto requirements, the EU will establish an internal market for carbon dioxide allowances from 2005, the EU Emissions Trading Scheme (ETS). National governments are to allocate most of these allowances for free.
Keats, K. Martinez, Neuhoff, K.
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source