Results 151 to 160 of about 396,234 (309)

EU working time directive [PDF]

BMJ, 2003
openaire   +1 more source

Impact of the EU Biofuels Directive on the EU food supply chain [PDF]

The paper investigates the impact of the EU Biofuels Directive (BFD) on the EU agri-food supply chain using the computable general equilibrium model of the world economy named LEITAP.
Banse, Martin, Tabeau, Andrzej A., van Meijl, Hans, Woltjer, Geert B.   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Freshwater habitats within the Natura 2000 network. [PDF]

Ecol Appl
Baattrup-Pedersen A, Baumane M, Nielsen A, Trolle D, Branco P, Borgwardt F, Hering D, Birk S.   +7 more
europepmc   +1 more source

EFFECTS OF A POTENTIAL NEW BIOFUEL DIRECTIVE ON EU LAND USE AND AGRICULTURAL MARKETS [PDF]

In its Progress Report on Biofuels the European Commission proposes a more restrictive biofuel directive which sets a mandatory minimum share of biofuels in total fuel consumption in the transport sector of 10% per Member State by 2020. This is likely to
Banse, Martin, Grethe, Harald
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Regulations for international non-proprietary name prescribing and substitution, relevant for cross-border ePrescribing and eDispensation services in the European Union. [PDF]

Eur J Public Health
Vander Stichele R, Roumier J, Van Nimwegen D, Kalra D, Kalra D, Gkogkidis A, Vegiotti N, Quintana Y, Wilson P.   +8 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Balancing the supply and demand for taxonomy: An analysis of European taxonomic capacity and policy needs. [PDF]

PLoS One
Groom QJ, De Nolf M, Estupinan-Suarez LM, Meeus S.   +3 more
europepmc   +1 more source

Audiovisual Media Services in the EU. Next Generation Approach or Old Wine in New Barrels? [PDF]

In this article, we analyse how the European legislator is currently responding to some of the recent changes in the media and communications environment with the adoption of the Audiovisual Media Services Directive.
David STEVENS, Eva LIEVENS, Evi WERKERS, Peggy VALCKE   +3 more
core