Results 181 to 190 of about 11,399,904 (367)

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora   +8 more
wiley   +1 more source

Modeling angiogenesis under Robin boundary conditions

open access: yesQuantitative Biology, Volume 13, Issue 4, December 2025.
Abstract In this study, we show an example of a numerical model based on the Keller–Segel system of equations to simulate angiogenesis in response to chemotaxis under Robin boundary conditions, which represent the presence of flux at the tumor. Different parameters of the model are modified to identify key biological factors relevant to the behavior of
Pablo Álvarez‐Caudevilla   +2 more
wiley   +1 more source

On the deep‐water and shallow‐water limits of the intermediate long wave equation from a statistical viewpoint

open access: yesTransactions of the London Mathematical Society, Volume 12, Issue 1, December 2025.
Abstract We study convergence problems for the intermediate long wave (ILW) equation, with the depth parameter δ>0$\delta > 0$, in the deep‐water limit (δ→∞$\delta \rightarrow \infty$) and the shallow‐water limit (δ→0$\delta \rightarrow 0$) from a statistical point of view.
Guopeng Li, Tadahiro Oh, Guangqu Zheng
wiley   +1 more source

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