Results 61 to 70 of about 164 (107)

Patient and healthcare provider experience of diroximel fumarate: considerations for selecting disease-modifying therapy

Neurodegenerative Disease Management
To evaluate treatment perceptions of diroximel fumarate (DRF) for relapsing multiple sclerosis (MS), with contextual data from dimethyl fumarate (DMF) users, based on patient and healthcare provider (HCP) surveys.A prospective web-based survey was conducted among MyMSTeam users aged ≥ 21 years in the United States, who provided information about their ...
Cortnee Roman, Meghan Garabedian, Virginia R. Schobel, Beth Schneider, Elizabeth Luce, Jason P. Mendoza, James B. Lewin, Sai L. Shankar   +7 more
openaire   +2 more sources

Safety and effectiveness of diroximel fumarate in relapsing forms of multiple sclerosis: a systematic review and meta-analysis

Neurological Sciences
Abstract Objective To evaluate the safety and efficacy of Diroximel Fumarate (DRF) in patients with different relapsing forms of MS (RMS) through systematic review and meta-analysis. Methods A systematic review and meta-analysis adhering to PRISMA guidelines was conducted.
Haneen Sabet, Mohamed Ahmed Zanaty, Abdelfattah Arafa, Mohamed El-Moslemani, Shereen Mohamed Olama, Mahmoud G. A. Saleh, Abdallah Abbas, Ahmed Z. Obeidat   +7 more
openaire   +2 more sources

METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD DIROXIMEL FUMARATE IN BULK DRUG AND IT'S DOSAGE FORM

, 2023
A Diroximel Fumarate is clinically used in combination in the treatment of anti-inflammatory agent. The present work deals with the RP-HPLC methods for Diroximel Fumarate in pharmaceutical formulation. attempts were made to develop rp-hplc method for estimation of diroximel fumarate bulk drug and formulation For the rp hplc method, agilent (s.k ...
openaire   +1 more source

Derivados do ácido fumárico utilizados no tratamento de esclerose múltipla: um overview

, 2021
Produtos naturais são substâncias resultantes do metabolismo secundário dos seres vivos. Diferentemente dos metabolitos primários, são particulares de espécies ou gêneros específicos. Plantas, fungos, bactérias e organismos marinhos
Esteves, Arthur Caputo [UNIFESP]
core  

Assessing neuroprotective effects of diroximel fumarate and siponimod via modulation of pacemaker channels in an experimental model of remyelination

Experimental Neurology
Cuprizone (CPZ)-induced alterations in axonal myelination are associated with a period of neuronal hyperexcitability and increased activity of hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels in the thalamocortical (TC) system.
Laura, Vinnenberg, Nicole, Rychlik, Tengiz, Oniani, Brandon, Williams, John A, White, Stjepana, Kovac, Sven G, Meuth, Thomas, Budde, Petra, Hundehege   +8 more
openaire   +2 more sources

Efficacy and safety of multiple sclerosis drugs approved since 2018 and future developments

, 2022
Multiple sclerosis treatment made substantial headway during the last two decades with the implementation of therapeutics with new modes of action and routes of application.
Faissner, Simon Raoul (Prof. Dr. med.), Gold, Ralf (Prof. Dr. med.)   +1 more
core  

Diroximel fumarate for multiple sclerosis

Australian Prescriber, 2022
openaire   +2 more sources

Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysis [PDF]

Background: Different therapeutic strategies are available for the treatment of people with relapsing-remitting multiple sclerosis (RRMS), including immunomodulators, immunosuppressants and biological agents.
Ridley B., Peryer G., Gonzalez-Lorenzo M., Piggott T., Filippini G., Del Giovane C., Foschi M., Minozzi S., Tramacere I., Baldin E., Nonino F.   +10 more
core   +2 more sources

Diroximel Fumarate in Patients with Relapsing-Remitting Multiple Sclerosis: NEDA-3 After Re-Baselining in the Phase 3 EVOLVE-MS-1 Study.

INTRODUCTION: Diroximel fumarate (DRF) and dimethyl fumarate (DMF) are orally administered fumarate disease-modifying therapies (DMTs) for multiple sclerosis (MS).
Hunter, Samuel, Hunter, Samuel F, Chen, Hailu, Bowen, James, Then Bergh, Florian, Lewin, James, Bowen, J D, Lewin, James B, Stulc, Jessica, Scaramozza, Matthew, Bozin, Ivan   +10 more
core   +1 more source

The Evolving Role of Monomethyl Fumarate Treatment as Pharmacotherapy for Relapsing-Remitting Multiple Sclerosis

Multiple sclerosis is the most common autoimmune disease affecting the central nervous system (CNS) worldwide. Multiple sclerosis involves inflammatory demyelination of nerve fibers in the CNS, often presenting with recurrent episodes of focal sensory or
Le, Viet, Anderson, Lillian, Mosieri, Chizoba N, Boggio, Nicole A, Ahmadzadeh, Shahab, Paladini, Antonella, Kaye, Adam M, Lacey, John, Varrassi, Giustino, Robinson, Christopher L, Askins, Dorothy H, Kaye, Alan D, Fazal, Ahmed, Shekoohi, Sahar   +13 more
core   +1 more source