Results 1 to 10 of about 687 (125)
Pharmaceutics, 2022 (1) Background: In their 60-year history, dimethyl fumarate and other salts of fumaric acid have been used for the treatment of psoriasis and other immune-mediated diseases for their immune-modulating properties.
Matteo Paolinelli +2 more
exaly +3 more sources
Dimethyl fumarate transfer into human milk
Therapeutic Advances in Neurological Disorders, 2020 Dimethyl fumarate (DMF) is approved for the treatment of relapsing-remitting multiple sclerosis. It is unknown whether DMF or its primary metabolite monomethyl fumarate (MMF) are excreted into human milk.
Andrea I Ciplea +2 more
exaly +2 more sources
Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?
Pharmaceuticals, 2020 Fumaric acid esters (FAEs) are small molecules with anti-oxidative, anti-inflammatory and immune-modulating effects. Dimethyl fumarate (DMF) is the best characterised FAE and is approved and registered for the treatment of psoriasis and Relapsing ...
Stephanie Kourakis +2 more
exaly +3 more sources
Hospital Pharmacy, 2013 Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Cada, Dennis J +2 more
openaire +4 more sources
Real-world discontinuation rate of teriflunomide and dimethyl fumarate in multiple sclerosis
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2021 Background For patients with MS, medication switches increase the risk of disease reactivation. Objective Compare discontinuation rates due to treatment failure or side effects between teriflunomide and dimethyl fumarate, and investigate clinical ...
Hilde Norborg +4 more
doaj +1 more source
Communications Biology, 2023 Dimethyl fumarate is an ester from the Krebs cycle intermediate fumarate. This drug is approved and currently used for the treatment of psoriasis and multiple sclerosis, and its anti-angiogenic activity was reported some years ago.
Mª Carmen Ocaña +11 more
doaj +1 more source
Safety and efficacy of dimethyl fumarate in ALS: randomised controlled study
Annals of Clinical and Translational Neurology, 2021 Objective Neuroinflammation is an important pathogenic mechanism in amyotrophic lateral sclerosis (ALS), with regulatory T cells (Tregs) mediating a slower rate of disease progression.
Steve Vucic +6 more
doaj +1 more source
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2023 Background Sleep disorders are common in patients with multiple sclerosis and have a bidirectional interplay with fatigue and depression. Objective To evaluate the effect of treatment with oral dimethyl fumarate on the quality of sleep in relapsing ...
Giancarlo Comi +14 more
doaj +1 more source
Molecular Pain, 2022 Osteoarthritis (OA), a chronic degenerative disease, leads to pain and loss of function. Existing treatments for OA pain have limited efficacy and show significant side effects.
Shao-Jie Gao +8 more
doaj +1 more source
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2022 Background Comparing real-world effectiveness and tolerability of therapies for relapsing-remitting multiple sclerosis is increasingly important, though average treatment effects fail to capture possible treatment effect heterogeneity.
Gabrielle Simoneau +10 more
doaj +1 more source