Results 41 to 50 of about 893,441 (290)
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Learning together: The dynamics of training teachers for disability inclusion in South Africa
Frontiers in Education, 2022 Despite the need for inclusive education in South Africa, many teachers have not been appropriately trained for the inclusion process for learners with disabilities in classrooms.
Kofi Nseibo +5 more
doaj +1 more source
What Do We See: An Investigation Into the Representation of Disability in Video Games [PDF]
arXiv, 2021 There has been a large body of research focused on the representation of gender in video games. Disproportionately, there has been very little research in respect to the representation of disability. This research was aimed at examining the representation of disabled characters through a method of content analysis of trailers combined with a survey of ...
arxiv
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Improved Web Accessibility Evaluation of Open Learning Contents for Individuals with Learning Disabilities [PDF]
arXiv, 2023 Web content should be accessible to normal and disabled communities on electronic devices. The Web Accessibility Initiative (WAI) has created standard guidelines called Web Content Accessibility Guidelines (WCAG). Mobile Web Best Practice (MWBP) is also proposed by WAI for accessibility of websites on desktop computers and mobile devices like ...
arxiv
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Frontiers in Psychology, 2023 ObjectiveThe aim of the present study was to assess the validity of the Ease of Language Understanding (ELU) model through a statistical assessment of the relationships among its main parameters: processing speed, phonology, working memory (WM), and dB ...
Lina Homman +5 more
doaj +1 more source
Accessibility and Inclusiveness of New Information and Communication Technologies for Disabled Users and Content Creators in the Metaverse [PDF]
arXiv, 2023 Despite the proliferation of Blockchain Metaverse projects, the inclusion of physically disabled individuals in the Metaverse remains distant, with limited standards and regulations in place. However, the article proposes a concept of the Metaverse that leverages emerging technologies, such as Virtual and Augmented Reality, and the Internet of Things ...
arxiv
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
A Democratic Platform for Engaging with Disabled Community in Generative AI Development [PDF]
arXiv, 2023 Artificial Intelligence (AI) systems, especially generative AI technologies are becoming more relevant in our society. Tools like ChatGPT are being used by members of the disabled community e.g., Autistic people may use it to help compose emails. The growing impact and popularity of generative AI tools have prompted us to examine their relevance within
arxiv