Results 131 to 140 of about 974,850 (342)

Accessible Environment for Young People with Disabilities in St Petersburg: Sociological Analysis

open access: yesДискурс
Introduction. The article is devoted to the opportunities and barriers of the environment. It is proposed to look at the creation of an “accessible environment” not only as the elimination of physical barriers, but also from the point of view of its ...
O. A. Novozhilova
doaj   +1 more source

Understanding quality in inclusive research: a process of dialogue

open access: yes, 2013
The case for research by and with (rather than on) people with learning disabilities has been successfully made. Calls for emancipatory research have drawn attention to the ways that research owned by disabled people can better tackle social oppression ...
Nind, Melanie
core  

Disabled parents' involvement in their children's education: an examination of good practice [PDF]

open access: yes, 2009
This report comes at the end of an 11 month study exploring disabled parents' experiences of involvement in their children's education. Supporting parents' participation in their children's schooling has been a government goal for decades.
Brunner, Richard   +3 more
core  

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

open access: yesAdvanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar   +7 more
wiley   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

open access: yesAdvanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang   +18 more
wiley   +1 more source

Disability and Disability Culture

open access: yes, 2017
Social work has a rich history in working for the rights of people in society. The profession’s commitment to vulnerable and oppressed people and groups are codified in national and international ethical standards. Social justice and respecting the dignity and worth of people are core ethical principles.
Romel W. Mackelprang, Ryan Parrey
openaire   +1 more source

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou   +5 more
wiley   +1 more source

Supporting disabled parents' involvement in their children's education. Good practice guidance for schools [PDF]

open access: yes, 2009
In this guidance you will find the voices of a range of disabled parents describing how good practice in schools has helped them to be involved in their children's education. The guidance is based on the findings of a research project. It is intended for
Brunner, Richard   +3 more
core  

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang   +12 more
wiley   +1 more source

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