Results 31 to 40 of about 136,307 (268)

Disturbance of the stato-dynamic function in patients with foot amputation defects and their compensation by prosthetic orthopedic products

open access: yesГений oртопедии, 2018
Material and methods The article discusses the features of the changes in the dynamic characteristics of the foot-support interaction in patients with foot amputation defects that reflect the state of their stato-dynamic function and the success of ...
Andrei A. Trofimov   +3 more
doaj   +1 more source

CIVILIZATIONAL IDENTITY OF RUSSIAN STUDENT YOUTH IN A DIGITAL SOCIETY

open access: yesВестник университета, 2020
The modern concept of civilization, processes of civilizational identification and identity on the basis of allocation of basic values have been considered. Traditional spiritual and moral values of Russian population have been studied.
V. V. Maximov, E. A. Malakhova
doaj   +1 more source

Acceptance of Industrial Collaborative Robots by People With Disabilities in Sheltered Workshops

open access: yesFrontiers in Robotics and AI, 2021
The integration of people with disabilities into the working world is an important, yet challenging field of research. While different inclusion efforts exist, people with disabilities are still under-represented in the open labor market.
Sandra Drolshagen   +5 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

More than a ramp

open access: yesForced Migration Review, 2010
"People with disability live in families and live in communities. We cannot be separated from society.” Simon Ong’om, Chairperson of the Gulu Disabled Persons Union (GDPU)
Gulu Disabled Persons Union
doaj  

The Interzonal Distribution of the Load on the Plantar Surface of the Foot During Walking in the Patients with Cerebral Palsy as an Objective Criterion of Functional Impairment Severity

open access: yesTravmatologiâ i Ortopediâ Rossii, 2020
Relevance. The main direction of rehabilitation of children with cerebral palsy is the preservation and enhancement of the existing level of support and locomotion, as well as compensation of its impairment through various methods of rehabilitation.
L. M. Smirnova   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Madness as disability

open access: yesHistory of Psychiatry, 2014
How does society imagine mental illness? Does this shift radically over time and with different social attitudes as well as scientific discoveries about the origins and meanings of mental illness? What happens when we begin to think about mental illness as madness, as a malleable concept constantly shifting its meaning?
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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