Results 51 to 60 of about 225,270 (313)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

More than a ramp

open access: yesForced Migration Review, 2010
"People with disability live in families and live in communities. We cannot be separated from society.” Simon Ong’om, Chairperson of the Gulu Disabled Persons Union (GDPU)
Gulu Disabled Persons Union
doaj  

Disturbance of the stato-dynamic function in patients with foot amputation defects and their compensation by prosthetic orthopedic products

open access: yesГений oртопедии, 2018
Material and methods The article discusses the features of the changes in the dynamic characteristics of the foot-support interaction in patients with foot amputation defects that reflect the state of their stato-dynamic function and the success of ...
Andrei A. Trofimov   +3 more
doaj   +1 more source

The Interzonal Distribution of the Load on the Plantar Surface of the Foot During Walking in the Patients with Cerebral Palsy as an Objective Criterion of Functional Impairment Severity

open access: yesTravmatologiâ i Ortopediâ Rossii, 2020
Relevance. The main direction of rehabilitation of children with cerebral palsy is the preservation and enhancement of the existing level of support and locomotion, as well as compensation of its impairment through various methods of rehabilitation.
L. M. Smirnova   +2 more
doaj   +1 more source

Sanitation resources for disabled individuals in Uganda

open access: yesSouth Sudan Medical Journal, 2022
The material presented in this paper was derived from research on sources of current literature that address global sanitation problems, especially in Uganda. Information gathered from interviews with Ugandans provided a vital component.
Harrison Schmachtenberger   +2 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Acceptance of Industrial Collaborative Robots by People With Disabilities in Sheltered Workshops

open access: yesFrontiers in Robotics and AI, 2021
The integration of people with disabilities into the working world is an important, yet challenging field of research. While different inclusion efforts exist, people with disabilities are still under-represented in the open labor market.
Sandra Drolshagen   +5 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Governor's Committee for Disabled Persons Report [PDF]

open access: yes, 1989
Newsletter issued by the Texas Governor's Committee for Disabled Persons discussing news, events, statistics, and other relevant information related to the employment, advocacy, and lives of Texans with ...
Texas Governor's Committee for Disabled Persons   +1 more
core  

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

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