Results 41 to 50 of about 848,368 (315)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Interzonal Distribution of the Load on the Plantar Surface of the Foot During Walking in the Patients with Cerebral Palsy as an Objective Criterion of Functional Impairment Severity

open access: yesTravmatologiâ i Ortopediâ Rossii, 2020
Relevance. The main direction of rehabilitation of children with cerebral palsy is the preservation and enhancement of the existing level of support and locomotion, as well as compensation of its impairment through various methods of rehabilitation.
L. M. Smirnova   +2 more
doaj   +1 more source

Pedagogic competence of teachers in religious moderation-based islamic education for disabled students

open access: yesJPPI (Jurnal Penelitian Pendidikan Indonesia), 2022
This study explored: 1) the understanding and skills of teachers in managing PAI learning based on religious moderation for people with disabilities; 2) the form of religious moderation in the teaching of PAI based on religious moderation for people with
Mindani Mindani   +2 more
doaj   +1 more source

National Association of Disabled Staff Networks (NADSN) – “Our Stories: Experiences from our Disabled Staff Networks across the UK” [PDF]

open access: yes, 2016
The National Association of Disabled Staff Networks (NADSN) held a panel session at the National Association of Disability Practitioners (NAPD) 2015 annual conference to share experiences from Disabled Staff Networks across the UK.
Nicholson, Jacquie   +2 more
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

More than a ramp

open access: yesForced Migration Review, 2010
"People with disability live in families and live in communities. We cannot be separated from society.” Simon Ong’om, Chairperson of the Gulu Disabled Persons Union (GDPU)
Gulu Disabled Persons Union
doaj  

Disturbance of the stato-dynamic function in patients with foot amputation defects and their compensation by prosthetic orthopedic products

open access: yesГений oртопедии, 2018
Material and methods The article discusses the features of the changes in the dynamic characteristics of the foot-support interaction in patients with foot amputation defects that reflect the state of their stato-dynamic function and the success of ...
Andrei A. Trofimov   +3 more
doaj   +1 more source

CIVILIZATIONAL IDENTITY OF RUSSIAN STUDENT YOUTH IN A DIGITAL SOCIETY

open access: yesВестник университета, 2020
The modern concept of civilization, processes of civilizational identification and identity on the basis of allocation of basic values have been considered. Traditional spiritual and moral values of Russian population have been studied.
V. V. Maximov, E. A. Malakhova
doaj   +1 more source

Sanitation resources for disabled individuals in Uganda

open access: yesSouth Sudan Medical Journal, 2022
The material presented in this paper was derived from research on sources of current literature that address global sanitation problems, especially in Uganda. Information gathered from interviews with Ugandans provided a vital component.
Harrison Schmachtenberger   +2 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

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