Results 91 to 100 of about 1,026,916 (276)
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Recombination fluorescence in ultracold neutral plasmas
, 2007 We present the first measurements and simulations of recombination fluorescence in ultracold neutral plasmas. In contrast with previous work, experiment and simulation are in significant disagreement.
Bergeson, S. D., Robicheaux, F.
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Consensos sobre la naturaleza de la ciencia: fundamentos de una investigación empírica [PDF]
Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2007 The issues about the nature of science are today considered a core content of the scientific and technological literacy for all. However, the inclusion of the nature of science in the science school curriculum is not easy and requires some conditions ...
Acevedo-Díaz, J.A.; +3 more
doaj
Evolution of the interpersonal conflict paradigm
Judgment and Decision Making, 2008 Using Brunswik’s (1952) lens model framework, Hammond (1965) proposed interpersonal conflict theory to explain the nature, source, and resolution of disagreement or “cognitive conflict” between parties performing judgment tasks.
Mandeep K. Dhami, Henrik Olsson
doaj +1 more source
Disagreement and security design [PDF]
, 2018 We study optimal security design when the issuer and market participants agree to disagree about the characteristics of the asset to be securitized.
Ortner, Juan, Schmalz, Martin C.
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
What is the Epistemic Significance of Disagreement? [PDF]
, 2019 Over the past decade, attention to epistemically significant disagreement has centered on the question of whose disagreement qualifies as significant, but ignored another fundamental question: what is the epistemic significance of disagreement?
Martin, Noah Gabriel
core