Results 101 to 110 of about 1,033,986 (310)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

The Epistemology of Disagreement [PDF]

open access: yes
Short introduction to the epistemology of ...
Frances, Bryan
core  

Who’s Afraid of Disagreement about Disagreement?

open access: yesInternational Journal of Philosophical Studies, 2023
This paper is not concerned with the (amply discussed) question as to the rational response to peer disagreement. Instead, it addresses a (considerably less often debated) problem to which many views about the (epistemic) significance of disagreement are vulnerable (to some extent or another): the problem of self-undermining.
openaire   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

La política deliberativa y las “virtudes” del procedimiento. Un análisis crítico del procedimentalismo de Habermas [PDF]

open access: yesRevista Enfoques, 2013
Habermas aims to overcome the debate between liberalism and republicanism by integrating elements from both traditions and trying to outline a procedural understanding of democracy.
Vicente Montenegro Bralic
doaj  

A pragmatic argument against equal weighting [PDF]

open access: yes, 2019
We present a minimal pragmatic restriction on the interpretation of the weights in the “Equal Weight View” regarding peer disagreement and show that the view cannot respect it. Based on this result we argue against the view.
Nissan-Rozen, Ittay, Spectre, Levi
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Adjudication in the Age of Disagreement [PDF]

open access: yes, 2017
In the time I have here with you today I would like to offer the beginnings of an answer. It does not lie in the distance between the court’s traditions and Manton’s conduct. That would be too easy.
Witt, John Fabian
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Religious Disagreement in Analytic Theology

open access: yesSt Andrews Encyclopaedia of Theology
Religious disagreement means holding incompatible views of the truth or of the plausibility of some position that is religiously relevant. It is well known that many religious and non-religious worldviews make apparently incompatible claims about ...
Olli-Pekka Vainio
doaj  

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