Results 111 to 120 of about 1,303,041 (346)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structured outflow from a dynamo active accretion disc

, 2002
We present an axisymmetric numerical model of a dynamo active accretion disc. If the dynamo-generated magnetic field in the disc is sufficiently strong (close to equipartition with thermal energy), a fast magneto-centrifugally driven outflow develops ...
Brandenburg, Axel, Dobler, Wolfgang, Shukurov, Anvar, von Rekowski, Brigitta   +3 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Imaginal discs [PDF]

Current Biology, 2010
Aldaz, Silvia, Escudero, Luis M.
openaire   +2 more sources

Optic Disc Anomalies with Excavation in the Disc (Optic Disc Pit, Morning Glory Disc Anomaly, Optic Disc Coloboma, Peripapillary Staphyloma)

Güncel Retina Dergisi (Current Retina Journal), 2022
Optic disc pits, optic disc coloboma, morning glory disc anomaly, and peripapillary staphyloma are the leading optic disc anomalies with excavation in the disc. These anomalies can be seen together with some syndromes and in this case, can be evaluated as part of the spectrum of the disease.
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Features of the Design and Manufacturing Techniques of Frictional Disks of Caterpillar and Wheel Cars

Механика машин, механизмов и материалов, 2016
Most often meeting reason of failure while in service frictional brakes and frictional knots in caterpillar and wheel cars is deformability of frictional disks. Deformability of disks leads to indistinct inclusion and deenergizing of the frictional knot,
Vladimir E. Antonyuk
doaj  

Dental Implants with External Hex Inclined Shoulder in Full-Arch Immediate Loading Rehabilitations of the Maxilla

Dentistry Journal
Background: Coaxial implants with an inclined neck might overcome some problems related to angulation of the implant axis when using tilted implants. Therefore, the aim of the present work was to conduct a narrative review of the current literature and ...
Francesco Bagnasco, Paolo Pesce, Domenico Baldi, Francesco Motta, Francesco Pera, Nicola De Angelis, Maria Menini   +6 more
doaj   +1 more source

Adjacent disc and facet joint degeneration in young adults with low-grade spondylolytic spondylolisthesis: A magnetic resonance imaging study

Journal of the Formosan Medical Association, 2015
Premature adjacent-level degeneration has been attributed to vertebral fusion, but spondylolisthesis has not been reported as a pathological factor responsible for the degeneration of adjacent disc and facet joint.
Chin-Chiang Hsieh, Jung-Der Wang, Ruey-Mo Lin, Chii-Jeng Lin, Kuo-Yuan Huang   +4 more
doaj   +1 more source

LUMBAR DISC HERNIATION

Revista Brasileira de Ortopedia (English Edition), 2010
Lumbar disc herniation is the most common diagnosis among the degenerative abnormalities of the lumbar spine (affecting 2 to 3% of the population), and is the principal cause of spinal surgery among the adult population. The typical clinical picture includes initial lumbalgia, followed by progressive sciatica.
Vialle, Luis Roberto, Vialle, Emiliano Neves, Suárez Henao, Juan Esteban, Giraldo, Gustavo   +3 more
openaire   +2 more sources