Results 141 to 150 of about 1,617,242 (349)

AcDc - A new code for the NLTE spectral analysis of accretion discs: application to the helium CV AM CVn

open access: yes, 2004
We present a recently developed code for detailed NLTE calculations of accretion disc spectra of cataclysmic variables and compact X-ray binaries. Assuming a radial structure of a standard alpha-disc, the disc is divided into concentric rings.
Barnard   +37 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Features of the Design and Manufacturing Techniques of Frictional Disks of Caterpillar and Wheel Cars

open access: yesМеханика машин, механизмов и материалов, 2016
Most often meeting reason of failure while in service frictional brakes and frictional knots in caterpillar and wheel cars is deformability of frictional disks. Deformability of disks leads to indistinct inclusion and deenergizing of the frictional knot,
Vladimir E. Antonyuk
doaj  

Two-dimensional transient problem for a thick disc with internal heat source [PDF]

open access: yesFME Transactions, 2010
The problem treated here is to determine thermo-elastic stress in a thick disc due to interior heat generation within the solid, under thermal boundary condition, which is subjected to arbitrary initial temperature on the upper and lower face at zero ...
Vargeze Vinod, Kalsa Lalsing
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Vinyles et cassettes : Philip K. Dick et la reproduction du son

open access: yesReS Futurae
There are few sf writers who were more deeply involved in music than Philip K. Dick. It is not just a matter of the numberless quotations of music pieces in his novels and stories ; Dick explored like no other the possibilities of music in its most ...
Umberto Rossi
doaj   +1 more source

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