Results 31 to 40 of about 260,516 (241)
Chinese Journal of Mechanical Engineering, 2023 The operation of a shield tunnel boring machine (TBM) in a high-strength hard rock stratum results in significant cutter damage, adversely affecting the thrust and torque of the cutter head.
Hua Jiang +4 more
doaj +1 more source
An investigation into the fertilizer particle dynamics off-the-disc [PDF]
, 2015 The particle size range specifications for two biosolids-derived organomineral fertilizers (OMF) known as OMF10 (10:4:4) and OMF15 (15:4:4) were established.
Miller, P. C. H. +5 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
LubricantsThe large-diameter slurry tunnel boring machine (TBM) is widely used in the construction of tunnels across rivers and seas. However, cutter wear has become a critical issue that severely limits the tunnelling efficiency.
Yingran Fang +4 more
doaj +1 more source
The Analysis of the Parameters of Rock Cutting by Disc Cutter Based on ANSYS [PDF]
, 2020 . When TBM tunneling, the disc cutter directly in contact with the rock. The disc cutter is an important component of the TBM, so the numerical simulation study of disc cutter breaking rock process is established.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Development Process of Cutter Ring for Shield Machine/Tunnel Boring Machine （TBM） Hob [PDF]
TeshugangThe disc cutter is the key component of the shield machine， and it is also the most easily worn and failed component in the tunneling construction process. The wear of the disc cutter ring is mainly composed of three types of abrasive wear， adhesive wear
Cao Yulong +4 more
doaj +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Simulation of Disc Cutter Loads Based on ANSYS/LS-DYNA
, 2011 In order to solve serious damage of pick on part-face tunnel machine during hard rock cutting, explore the applicability of disc cutter on the machine, the structure of disc cutter was designed, a model of dist cutter was built with Pro/E software ...
Wei Du +3 more
core +1 more source