Results 51 to 60 of about 89,378 (260)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Changes in the production and use of pottery from the Early Neolithic to the ‘secondary products revolution’: some evidence from LN Makriyalos, Northern Greece

Documenta Praehistorica, 2002
Recent developments in pottery studies have altered the way archaeologists handle and interpret prehistoric pottery. The technology and use of pottery, the symbolic and social meaning of the pot are considered as anthropological phenomena, the products ...
Dimitrios Vlachos
doaj   +1 more source

Uptake and barriers for implementation of the resect and discard strategy: an international survey

Endoscopy International Open, 2020
Background and study aims Optical real-time diagnosis (= resect-and-discard strategy) is an alternative to histopathology for diminutive colorectal polyps. However, clinical adoption of this approach seems sparse.
Philippe Willems, Roupen Djinbachian, Saskia Ditisheim, Sinan Orkut, Heiko Pohl, Alan Barkun, Mickael Bouin, Bernard Faulques, Daniel von Renteln   +8 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

No deleterious circumference effects for T90 codends in an Australian fish trawl targeting tiger flathead, Platycephalus richardsoni

Frontiers in Marine Science
In an attempt to improve the selectivity of Australian fish trawls targeting tiger flathead, Platycephalus richardsoni (≥28 cm total length), the utility of four-seam codends with shortened lastridge ropes and comprising 71-mm meshes turned 90° (T90 ...
Matt K. Broadhurst, Matt K. Broadhurst, Russell B. Millar   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A 5-year cross-sectional retrospective analysis of discard of blood and its components in the blood bank of a tertiary trauma center

Asian Journal of Transfusion Science
INTRODUCTION: Blood transfusion is an integral part of health-care system and there is no complete suitable substitute for human blood till date. Thus, every unit of blood and its products is precious and should be used judiciously.
Arundhathi Shankaralingappa, K Shanti Jyoti, Thirunavukkarasu Arun Babu   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Reducing Artisanal Fishery Impact on Marine Community: New Data from Comparison of Innovative and Traditional Gear

Fishes
Fishery resources overexploitation, together with bycatch and discards, have an impact on marine ecosystems. The adoption of technologically innovative gears is a possible solution to reduce the discard and to enhance the sustainability of fishery ...
Manfredi Madia, Massimiliano Bottaro, Tiziana Cillari, Andrea Li Vorsi, Luca Castriota, Maria Rita Amico, Sergio Bizzarri, Teresa Maggio, Manuela Falautano, Michele Gristina, Ilaria Di Lauro, Floriana Trova, Patrizia Perzia, Roberto D’Ambra, Enrico Casola, Mauro Sinopoli   +15 more
doaj   +1 more source

Linking trawl fleet dynamics and the spatial distribution of exploited species can help to avoid unwanted catches: the case of the NW Mediterranean fishing grounds

Scientia Marina, 2018
With the full implementation of the landing obligation on 1 January 2019, In European waters it will become mandatory for the trawling fleet to land at port all catches of certain species because, according to Article 15 of the new European Common ...
Alfredo Garcia-de-Vinuesa, Iván Sola, Federico Quattrocchi, Francesc Maynou, Montserrat Demes   +4 more
doaj   +1 more source