Results 31 to 40 of about 95,710 (300)

Trash to Treasure: An Up-to-Date Understanding of the Valorization of Seafood By-Products, Targeting the Major Bioactive Compounds

open access: yesMarine Drugs, 2023
Fishery production is exponentially growing, and its by-products negatively impact industries’ economic and environmental status. The large amount of bioactive micro- and macromolecules in fishery by-products, including lipids, proteins, peptides, amino ...
Vikash Chandra Roy   +6 more
doaj   +1 more source

Discard sampling of the Dutch Nephrops fishery in 2007-2008 [PDF]

open access: yes, 2009
Dit rapport bevat de resultaten van een bemonsteringsprogramme van discards (DCR programma) in de Nederlandse visserij op Noorse kreeft in de Noordzee in 2007 en 2008.
Helmond, A.T.M., van   +1 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Reconstructing past fisheries catches for large pelagic species in the Indian Ocean

open access: yesFrontiers in Marine Science, 2023
Comprehensive catch data are fundamental to support the sustainable management of large pelagic fisheries. However, catch data reported by the Indian Ocean Tuna Commission (IOTC) on behalf of its member countries currently under-represent the extent of ...
Kristina N. Heidrich   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Fishery discards: factors affecting their variability within a demersal trawl fishery. [PDF]

open access: yesPLoS ONE, 2012
Discards represent one of the most important issues within current commercial fishing. It occurs for a range of reasons and is influenced by an even more complex array of factors.
Jordan Feekings   +3 more
doaj   +1 more source

An assessment of scup (Stenotomus chrysops) and black sea bass (Centropristas striata) discards in the directed otter trawl fisheries in the Mid-Atlantic Bight [PDF]

open access: yes, 2005
This study was undertaken to re-assess the level of scup (Stenotomus chrysops) discards by weight and to evaluate the effect of various codend mesh sizes on the level of scup discards in the winter-trawl scup fishery. Scup discards were high in directed
Banta, Sarah E.   +3 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The black scabbardfish (Aphanopus carbo Lowe, 1839) fisheries from the Portuguese mainland and Madeira Island

open access: yesScientia Marina, 2009
For several decades, the black scabbardfish (Aphanopus carbo, Lowe 1839) has been a valuable resource for fishing communities in Madeira and more recently for those in mainland Portugal.
Pedro Bordalo-Machado   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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