Results 41 to 50 of about 18,140 (303)
Reconstructing past fisheries catches for large pelagic species in the Indian Ocean
Comprehensive catch data are fundamental to support the sustainable management of large pelagic fisheries. However, catch data reported by the Indian Ocean Tuna Commission (IOTC) on behalf of its member countries currently under-represent the extent of ...
Kristina N. Heidrich +3 more
doaj +1 more source
Discards and bycatch: A review of wasted fishing
Bycatch and discards are a significant issue for global fisheries, with discards considered unnecessary mortality and wasted fishing. Discards have declined due to more selective gear and changes in regulations, but data on discard rates and species ...
McKenzie, Jonathan, Lively, Julie A.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
For several decades, the black scabbardfish (Aphanopus carbo, Lowe 1839) has been a valuable resource for fishing communities in Madeira and more recently for those in mainland Portugal.
Pedro Bordalo-Machado +6 more
doaj +1 more source
The Impact of Fisheries Discards on Scavengers in the Sea [PDF]
A scavenger is an animal that feeds on dead animals (carrion) that it has not killed itself. Fisheries discards are often seen as an important food source for marine scavengers so the reduction of discards due to the Landing Obligation may affect their ...
Morato, Telmo +37 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Since 2015, the European Union gradually implemented the landing obligation (LO). This prohibits at-sea discarding of species under total allowable catch management.
Robert, Marianne +5 more
core +1 more source
Benchmarking global fisheries discards
Discarding by fisheries is one of the most wasteful human marine activities, yet we have few estimates of its scale. Reliable estimates of global discards are essential for sustainable fisheries management.
Perez Roda, A. +7 more
core +1 more source

