Results 51 to 60 of about 9,522 (251)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Discard sampling of the Dutch Nephrops fishery in 2007-2008 [PDF]

open access: yes, 2009
Dit rapport bevat de resultaten van een bemonsteringsprogramme van discards (DCR programma) in de Nederlandse visserij op Noorse kreeft in de Noordzee in 2007 en 2008.
Helmond, A.T.M., van   +3 more
core  

Discards and bycatch: A review of wasted fishing

open access: yes, 2023
Bycatch and discards are a significant issue for global fisheries, with discards considered unnecessary mortality and wasted fishing. Discards have declined due to more selective gear and changes in regulations, but data on discard rates and species ...
McKenzie, Jonathan, Lively, Julie A.
core   +1 more source

Fishery observers address arctic fishery discards

open access: yesEnvironmental Research Letters, 2020
Fishery observers are prevalent actors in the global effort to reduce discards in fisheries, but there remains considerable uncertainty about how effective they are.
Hunter T Snyder, James T Erbaugh
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The Impact of Fisheries Discards on Scavengers in the Sea [PDF]

open access: yes, 2018
A scavenger is an animal that feeds on dead animals (carrion) that it has not killed itself. Fisheries discards are often seen as an important food source for marine scavengers so the reduction of discards due to the Landing Obligation may affect their ...
Morato, Telmo   +37 more
core   +1 more source

Acceptance, Sensory Characterization and Consumption Contexts for Dehydrated Persimmon Slices, Chips, Leathers and Powder: A Consumer Study

open access: yesFoods, 2023
Valorization of persimmon discards is a current challenge for the food industry. Obtaining dehydrated persimmon products can be a good option, but studies are necessary to predict consumer responses before placing new products on the market.
Marina Castillo   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

By-catch species susceptibilities and potential for survival in Algarve (southern Portugal) deep-water crustacean trawl fishery

open access: yesScientia Marina, 2018
Bottom trawling for crustaceans in Portuguese coastal waters is an important fishery in terms of revenue, despite its negative impacts on deep-sea ecosystems.
Ana C. Adão   +3 more
doaj   +1 more source

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