Results 51 to 60 of about 12,222 (259)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Comparison of diamond- and square-mesh codends in the hake (Merluccius merluccius L. 1758) trawl fishery of the Adriatic Sea (central Mediterranean)

Scientia Marina, 2008
A traditional codend (40 mm diamond mesh) and an experimental codend (40 mm square mesh) made of 2.6 mm diameter knotless PA netting were tested on a commercial trawl net on a sandy-muddy bottom (~70 m depth) of the Adriatic sea in order to assess the ...
Alessandro Lucchetti
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Casting light on the European anchovy: from biology to conservation and industry

Frontiers in Ecology and Evolution
This manuscript explores the role of European anchovies (Engraulis encrasicolus) in the central Mediterranean Region, shedding light on their ecological significance, conservation challenges, and sustainable utilization.
Mirko Mutalipassi, Mirko Mutalipassi, Emanuele D’Anza, Mariagiulia Pugliano, Roberto Firmamento, Carola Murano, Carola Murano, Nadia Ruocco, Chiara Pennesi, Gabriele Procaccini, Teresa Romeo, Teresa Romeo, Antonio Terlizzi, Antonio Terlizzi, Antonio Terlizzi, Vincenzo Peretti   +15 more
doaj   +1 more source

The use of demersal trawling discards as a food source for two scavenging seabird species: a case study of an eastern Mediterranean oligotrophic marine ecosystem

Avian Research, 2018
Background The banning of fisheries discards by imposing an obligation to land unwanted catch constitutes a key point of the Common Fishery Policy reform proposed by the European Commission.
Georgios Karris, Vlasis Ketsilis-Rinis, Anastasia Kalogeropoulou, Stavros Xirouchakis, Athanasios Machias, Irida Maina, Stefanos Kavadas   +6 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Caracterización de las principales pesquerías del golfo San Jorge Patagonia, Argentina Characterization of the main fisheries in San Jorge Gulf, Patagonia, Argentina

Latin American Journal of Aquatic Research, 2012
En el golfo San Jorge se desarrollan varias actividades económicas de relevancia, entre ellas dos pesquerías industriales: la pesquería de merluza común (Merluccius hubbsi Marini, 1933) y la pesquería de langostino patagónico (Pleoticus muelleri Bate ...
María Eva Góngora, Diego González-Zevallos, Alejandro Pettovello, Luis Mendía   +3 more
doaj  

Insights from Fishery Discards: Age and Feeding Habits of Large-Scaled Gurnard (Lepidotrigla cavillone, Lacepède 1801) and Spiny Gurnard (Lepidotrigla dieuzeidei, Blanc & Hureau 1973) in the Gulf of Cádiz (SW Iberian Peninsula)

Fishes
Despite their ecological importance, discarded species with low commercial value are often overlooked in marine research. This study examined the age structure and feeding habits of the large-scaled gurnard (Lepidotrigla cavillone) and the spiny gurnard (
Carlos Rodríguez-García, Óscar Lago-Piñeiro, Jesica Sarmiento-Carbajal, Remedios Cabrera-Castro   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source