Results 71 to 80 of about 95,710 (300)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

On Macroscopic Complexity and Perceptual Coding [PDF]

, 2011
The theoretical limits of 'lossy' data compression algorithms are considered. The complexity of an object as seen by a macroscopic observer is the size of the perceptual code which discards all information that can be lost without altering the perception
Scoville, John
core  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Discard sampling of the Dutch beam trawl fleet in 2008 [PDF]

Resultaten van het discardbemonsteringsprogramma van de Nederlandse boomkorvisserij in de Noordzee in 2008. In 2008 zijn tien reizen op de Nederlandse boomkorschepen met een motorvermogen groter dan 300 PK vissend met een maaswijdte van 80 mm bemonsterd.
Helmond, A.T.M., van, Overzee, H.M.J., van   +1 more
core   +6 more sources

Relative efficiency of square-mesh codends in an artisanal fishery in southern Brazil Eficiencia relativa de copos de malla cuadrada en una pesquería artesanal del sur de Brasil

Latin American Journal of Aquatic Research, 2012
The relative efficiency of two square-mesh codend designs with the same circumference (~2 m) but different mesh sizes and materials (32 mm polyethylene-PE and 30 mm polyamide-PA) was tested in an artisanal shrimp trawl fishery in Paraná, southern Brazil.
Catarina N.S Silva¹, José H Dias, André P Cattani, Henry L Spach   +3 more
doaj  

Discards of Spanish trawler fleets operating in the Bay of Biscay in 2000

Scientia Marina, 2006
A stratified sampling programme by gear and port was carried out by observers on board vessels in 2000 to study the discard behaviour of trawler fleets operating off Spanish North Atlantic coasts. No relationship between discards in weight or numbers and
Laura Lema, Nélida Pérez, Hortensia Araujo   +2 more
doaj   +1 more source

Discards monitoring in the Gillnet Sole Fishery [PDF]

The Gillnet Sole Fishery Study Group started discards monitoring. Data were supposed to be collected in three different ways: Self-sampling, catch monitoring by means of onboard cameras (CCTV) and monitoring under the Data Collection ...
Couperus, A.S., Helmond, A.T.M., van, Quirijns, F.J.   +2 more
core   +1 more source

Incidental catches of pelagic megafauna by the EU pelagic fleet in the Mauritanian exclusive economic zone during the year 2001 : results extracted from the scientific observer program [PDF]

, 2003
The joint project between the Netherlands Institute for Fisheries Research (RIVO) and the Mauritanian Institute for Oceanography and Fisheries Research (IMROP) has been initiated in 1998 in order to strengthen Mauritania’s capacity for research on stocks
Hofstede, R., ter
core   +1 more source