Results 31 to 40 of about 904,642 (218)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bankfull values in gauge station cross sections of the Raba river – polish Carpathians [PDF]

open access: yesActa Scientiarum Polonorum. Formatio Circumiectus, 2017
This paper presents comparison of differents methods of bankfull discharge calculation. The methods used were: Gauckler-Manning [Chow 1959], Williams [1978], Wolman and Leopold [Leopold et al. 1964], Hey and Thorne [Thorne et al. 1997]. Calculations were
Tom Combal   +3 more
doaj   +1 more source

Runoff variations in the Yangtze River Basin and sub-basins based on GRACE, hydrological models, and in-situ data

open access: yesEarth and Planetary Physics, 2022
Water budget closure is a method used to study the balance of basin water storage and the dynamics of relevant hydrological components (e.g., precipitation, evapotranspiration, and runoff).
WeiLong Rao, WenKe Sun
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Continuity of medication information transfer and continuous medication supply during hospital-to-home transitions - nationwide surveys in hospital and community pharmacies after implementing new legal requirements in Germany

open access: yesBMC Health Services Research
Background While successful information transfer and seamless medication supply are fundamental to medication safety during hospital-to-home transitions, disruptions are frequently reported.
Sophia Klasing   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Energy Storage System Modelling For Hybrid Electric Vehicle [PDF]

open access: yesE3S Web of Conferences
The equivalent circuit model (ECM)-based traditional state-of-charge (SoC) estimate approaches combine all state variables into a single enhanced state vector.
Mohammed G.   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Coexistence of magnetism and ferroelectricity in the 2D inorganic molecular crystal SbI3•(S7N)3

open access: yesnpj Computational Materials
Two-dimensional inorganic molecular crystals (2D IMCs) represent a novel class of layered materials constructed from inorganic molecules through weak intermolecular interactions. Benefiting from their “LEGO-like” modular assembly nature, we intentionally
Jianpei Xing   +5 more
doaj   +1 more source

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