Results 41 to 50 of about 1,498,865 (292)

Glacierized headwater streams as aquifer recharge corridors, subarctic Alaska

Geophysical Research Letters, 2017
Arctic river discharge has increased in recent decades although sources and mechanisms remain debated. Abundant literature documents permafrost thaw and mountain glacier shrinkage over the past decades. Here we link glacier runoff to aquifer recharge via
A. K. Liljedahl, A. Gädeke, S. O'Neel, T. A. Gatesman, T. A. Douglas   +4 more
doaj   +1 more source

In‐Hospital and Postdischarge Mortality Among Patients With Acute Decompensated Heart Failure Hospitalizations Ending on the Weekend Versus Weekday: The ARIC Study Community Surveillance

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Hospital staffing is usually reduced on weekends, potentially impacting inpatient care and postdischarge coordination of care for patients with acute decompensated heart failure (ADHF).
Louisa A. Mounsey, Patricia P. Chang, Carla A. Sueta, Kunihiro Matsushita, Stuart D. Russell, Melissa C. Caughey   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Continuity of medication information transfer and continuous medication supply during hospital-to-home transitions - nationwide surveys in hospital and community pharmacies after implementing new legal requirements in Germany

BMC Health Services Research
Background While successful information transfer and seamless medication supply are fundamental to medication safety during hospital-to-home transitions, disruptions are frequently reported.
Sophia Klasing, Frank Dörje, Heike Hilgarth, Nadine Metzger, Ina Richling, Hanna M. Seidling   +5 more
doaj   +1 more source

Contribution of N2O emissions to the atmosphere from Indian monsoonal estuaries [PDF]

Tellus: Series B, Chemical and Physical Meteorology, 2013
Estuaries are known to contribute a significant amount of nitrous oxide (N2O) to the atmosphere; however, the contribution from the Indian estuaries is unknown.
Gijjapu Durga Rao, Vedula V. S. S. Sarma
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Bankfull values in gauge station cross sections of the Raba river – polish Carpathians [PDF]

Acta Scientiarum Polonorum. Formatio Circumiectus, 2017
This paper presents comparison of differents methods of bankfull discharge calculation. The methods used were: Gauckler-Manning [Chow 1959], Williams [1978], Wolman and Leopold [Leopold et al. 1964], Hey and Thorne [Thorne et al. 1997]. Calculations were
Tom Combal, Artur Radecki-Pawlik, Wiktoria Czech, Karol Plesiński   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Study of surface discharge behaviour at the oil-pressboard interface

, 2013
This thesis is concerned with the surface discharge behaviour at the oil-pressboard interface. For large transformers this is classified as a serious failure mode because it can lead to catastrophic failure under normal AC voltage operating conditions ...
Zainuddin, H
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source