Results 51 to 60 of about 904,642 (218)

An Experimental Study on the Luminescence of the Leader Channel During the Relaxation Process Before Restrike in a Positive 6 m Air Gap Discharge

open access: yesApplied Sciences
Restrike frequently occurs during the positive leader development of long-air-gap discharges. At present, however, its detailed physical process and mechanism remain unclear.
Yongchao Yang   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Experiences of Family Members of Patients Discharged from Intensive Care Unit: A Systematic Review of Qualitative Studies

open access: yesNursing Reports
Background: Improving the understanding of the post-discharge experiences of family members after their loved ones leave the Intensive Care Unit (ICU) is essential for developing effective follow-up strategies. These strategies are crucial for mitigating
Benedetta Basso   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Prevalence of wasting and associated factors among children aged 6–59 months in Habro district, Eastern Ethiopia: a cross-sectional study

open access: yesFrontiers in Nutrition
BackgroundGlobally, five million children under the age of five died in 2021. Asia and African countries contributed to 69% and 27.2% of wasting, respectively.
Sileshi Tilahun   +9 more
doaj   +1 more source

Streamflow Simulation and Assessing the Land Use Changes impacts on it (Case Study: Gol Gol Catchment in The Province of Ilam, Iran) [PDF]

open access: yesمهندسی منابع آب, 2016
The main purpose of this study was to simulate rainfall - runoff processes to assess the effects of land use changes on the runoff generation using the hydrological WetSpa model, and also to evaluate the accuracy of predicted daily discharge at the Gol ...
Somaye Mirzaee   +2 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Comparison of GPM and ARR Rain Distribution Patterns in Design Flood Simulation

open access: yesMedia Komunikasi Teknik Sipil
This study evaluates the performance of Global Precipitation Measurement (GPM) satellite-based rainfall data in comparison to Automatic Rainfall Recorder (ARR) data in forming rainfall distribution patterns and assessing its impact on flood discharge ...
Yunita Ayu Setiyowati   +2 more
doaj   +1 more source

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