Results 51 to 60 of about 3,446,684 (305)

Bankfull discharge and recurrence intervals in Irish rivers [PDF]

open access: yes, 2012
Different definitions of the bankfull condition in rivers are based on morphological characteristics, boundary conditions and geometrical properties.
Ahilan, Sangaralingam   +10 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Predicting death and readmission after intensive care discharge [PDF]

open access: yes, 2008
Background: Despite initial recovery from critical illness, many patients deteriorate after discharge from the intensive care unit (ICU). We examined prospectively collected data in an attempt to identify patients at risk of readmission or death after ...
B.H. Cuthbertson   +7 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Modeling discharge capacity of labyrinth weirs through a learning machine approach [PDF]

open access: yesJournal of Applied Research in Water and Wastewater, 2019
In this paper, the discharge coefficient of weirs is simulated by the extreme learning machine (ELM). To this end, seven different ELM models are introduced by the input parameters.
Mohammadali Izadbakhsh, Reza Hajiabadi
doaj   +1 more source

Discharge communication in the emergency department : on quantity- and content-definition and on the benefit of information structuring [PDF]

open access: yes, 2015
Health and diseases have always accompanied humans and are important topics to talk about. Appropriate communication, however, can only have an impact on one’s health if the essential content is transferred and if the message is sent in a way enabling ...
Ackermann, Selina
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Analysis of discharge rates in rectangular slit, ogee, and sharp-crested weirs

open access: yesFrontiers in Built Environment
Climate change has made flash floods increasingly common. It's crucial to have confidence in the structural integrity of dams during a flash flood. According to the International Commission on Large Dams (ICOLD), approximately one-third of dam failures ...
Hossein Sohrabzadeh Anzani   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Empirical investigation on the discharge capacity of an emergency ship lock

open access: yesShuili Shuiyun Gongcheng Xuebao
The emergency ship lock, an integral hydraulic structure within the Changshanjiang hub series, serves crucial roles in flood discharge, lock maintenance, and specialized shipping operations. Despite its significance, both domestically and internationally,
LIN Yanping   +3 more
doaj   +1 more source

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