Results 61 to 70 of about 3,446,684 (305)
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Experimental study on discharge capacity of street inlet in urban flooding
Shui kexue jinzhan, 2020 Urban flood disasters have occurred frequently in recent years in China, causing a serious threat to urban management and the safety of people and property.
Qian CHEN, Junqiang XIA, Boliang DONG
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 PbO2 thin film is essential for applications in lead acid batteries system. In this work, PbO2 thin films with different surface microstructure were fabricated through electrodeposition technique by controlling the deposition current density. Though PbO2
Xuan Zhao +3 more
doaj +1 more source
Calculation analysis on the discharge capacity of Piano Key weir and relative influencing factors
Shuili Shuiyun Gongcheng Xuebao, 2022 In recent years, the problem of insufficient discharge capacity of the existing hydraulic projects has become more and more serious due to the frequent occurrence of extreme floods.
LI Yanfu +4 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
International Journal of Electrochemical Science, 2018 Disordered spinel LiNi0.5Mn1.5O4 (LNMO) was successfully synthesised via a molten-salt method using a mixture of LiOH⋅H2O and LiNO3 salts. The precursor was annealed at 750, 850 or 950 °C for 12 h, and the effects of calcination temperature on the ...
Nabilah Mokhtar +2 more
doaj +1 more source
Machine Learning Strategies for Forecasting Discharge Capacity in Lithium-Ion Batteries with NCM Layered Cathode Material [PDF]
The nuanced grasp of determinants impacting discharge capacity stands as an imperative linchpin for propelling the evolution of lithium-ion batteries to new frontiers.
Guo-Jin, Cao
core +2 more sources
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source