Results 61 to 70 of about 232,000 (307)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Past and Present of Discharge Capacity Modeling for Spillways—A Swedish Perspective

open access: yesFluids, 2019
Most of the hydropower dams in Sweden were built before 1980. The present dam-safety guidelines have resulted in higher design floods than their spillway discharge capacity and the need for structural upgrades.
James Yang   +3 more
doaj   +1 more source

Exploring the experience of community adjustment following discharge from a low secure forensic unit [PDF]

open access: yes, 2011
Low secure forensic services have been identified as a common interface between inpatient care and care in the community. However, to date, no research has specifically explored the lived experience of discharge from such units.
Burgess, Sophie Louise Horrobin
core  

Discharge Capacity of Energy Storages as a Function of the Discharge Current–Expanding Peukert’s equation

open access: yes, 2022
In 1897 Wilhelm Peukert tested lead-acid batteries with constant current and observed that a single equation can describe the relationship between the discharge capacity of the battery and a constant discharge current.
Steger, Fabian   +2 more
core  

THE EFFECT OF RETURN PERIOD AND SEDIMENTATION ON THE CAPACITY OF RIVER DISCHARGE CAPACITY IN SAMARINDA CITY, EAST KALIMANTAN

open access: yes, 2022
Factors that affect flooding are due to the dense population that occupies the floodplain of the river, the city's drainage channel which has a relatively flat topography, the rapid development of housing in the floodplain area, the topography of the ...
Yayuk Sri Sundari, Sundari, Yayuk Sri
core   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Role of Electrochemical Precipitation Parameters in Developing Mixed-Phase Battery-Grade Nickel Hydroxide

open access: yesElectrochem
There is a high demand for nickel hydroxide as an engineering material used in the positive electrode of nickel metal hydride (Ni-MH) rechargeable batteries.
Chinmaya Kumar Sarangi   +4 more
doaj   +1 more source

Anfis to estimate discharge capacity of rectangular side weir

open access: yesProceedings of the Institution of Civil Engineers - Water Management, 2013
The adaptive neuro-fuzzy inference system (Anfis) is considered for flow over rectangular side weirs located on a straight channel as a substantial part of distribution channels in irrigation systems and treatment units. To estimate the outflow over a rectangular sharp-crested side weir, the discharge coefficient in the side weir equation needs to be ...
Kisi, Ozgur   +2 more
openaire   +2 more sources

Towards effective capacity planning in a perinatal network centre [PDF]

open access: yes, 2010
Objective: To study the arrival pattern and length of stay in a neonatal intensive care/high dependency unit (NICU/HDU) and special care baby unit (SCBU) and the impact of capacity shortage in a perinatal network centre.
Hawdon, J.   +13 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

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