Results 101 to 110 of about 108,296 (296)

Why the Gospel of John is Fundamental to Jesus Research (Chapter One of Jesus Research: The Gospel of John in Historical Inquiry)

open access: yes, 2019
The constellation of the Johannine riddles—theological, historical, literary—and their implications for understanding the Jesus of history as well as the Christ of faith, and thus the historical and religious basis of western civilization, comprises ...
Anderson, Paul N.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

From One Dialogue to Another: Johannine Polyvalence from Origins to Receptions

open access: yes, 2008
Throughout the ages, one of the primary mistakes committed in studying the Gospel of John has been to read the text monologically instead of dialogically. This error has often led some readers of the Fourth Gospel to “get it wrong,” needing correction by
Anderson, Paul N.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

THE INFLUENCING FACTS OF CAREER SUCCESS [PDF]

open access: yes
The career success it’s a combination between circumstances and the way one answers to the said. In order to have a successful career it is necessary a long term planning of the professional line to be carried out, as well as the anticipation of some ...
Drd. Bumbeneci Dorin   +1 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Making Disciples: The Effects of Technology Integration Coaching

open access: yes, 2012
This paper describes a pilot study of collegial coaching for technology integration at two private Christian schools. Two students nearing completion of a Master’s in Education in Curriculum and Instruction with a Specialization in Instructional ...
Brupbacher, Linda   +4 more
core  

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