Results 81 to 90 of about 108,296 (296)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Principles for Starting a Song-Writing Ministry [PDF]

, 2020
With the approval of Dr. Keith Currie and Dr. David Schmal, I have chosen to complete the Music & Worship Ministry Project as the Final Thesis for the Masters of Art in Music and Worship. The objective of the project is to produce an Extended Play Record
Li, Carson Ka Siu
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Bakhtin\u27s Dialogism and the Corrective Rhetoric of the Johannine Misunderstanding Dialogue: Exposing Seven Crises in the Johannine Situation (Chapter

, 2007
One of the most fascinating thinkers and literary theorists within the last century is the late Russian form critic Mikhail Bakhtin, whose theory of dialogism seeks to account for several levels of dialectical tension and interplay in great literature ...
Anderson, Paul N.
core  

The Resurrection of our Lord Series C [PDF]

, 1989
(Excerpt) Luke\u27s empty tomb story has several typically Lukan features. First, the scene has an aura of calm when compared to Mark\u27s report that the women ran away frightened and dumbstruck, or Matthew\u27s picture of the angel who comes and scares
Niedner, Frederick A, Jr.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Invitation to Become: A Phenomenological Analysis of a Master–Disciple Relationship

Religions
The contribution of this paper lies in its extension of the phenomenological insights of Martin Buber and Jean-Luc Marion—in particular, Buber’s philosophy of dialogue and the I–thou relation, and Marion’s articulation of saturated phenomenality—to the ...
Michelle Rebidoux
doaj   +1 more source

L'ascension et l'ivresse dans la poésie soufie de Cheikh Moussa Kâ [PDF]

Annales du Patrimoine, 2015
Cet article propose de revisiter les poèmes écrits en wolof par le soufi Cheikh Moussa Kâ, disciple de Cheikh Ahmadou Bamba. Le disciple et le maître ont tous deux évolué entre le XIXe et le XXe siècle, en Afrique de l’Ouest et plus particulièrement au ...
Dr Saliou Ndiaye
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source