Results 51 to 60 of about 15,769 (290)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Disciple Making: From Doubter to Disciple [PDF]
The theme of our 2024 Great Commission Research Network conference was “Disciple Making: from Doubter to Disciple.” Disciple making is the mission and call of the Church and therefore must be a priority for church leaders.
Ransom, Brad
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Master and disciple in Konjaku Monogatari-shū
Японские исследованияThe paper considers the theme of tutorship, which is one of the cross-cutting issues in Konjaku Monogatari-shū, a 12th century collection of setsuwa didactic tales.
M. V. Babkova, M. S. Kolyada
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Korelasi Konsep Kerajaan Allah dan Pemuridan dalam Injil Matius bagi Pemuridan Masa Kini
Veritas: Jurnal Teologi dan Pelayanan, 2019 Di dalam gereja/persekutuan terjadi gejala banyak yang mengaku Kristen, tetapi sedikit yang mau dimuridkan. Namun, faktor penyebab utama masalah pemuridan di gereja justru berasal dari dalam Kekristenan sendiri. Ada dikotomi antara “menjadi orang percaya”
Sandra Wisantoso
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Evangelism or Disciple-Making? [PDF]
, 2013 Evangelistic “success” is often defined by the number of “decisions for Christ”—those who raise their hands . . . come to the altar . . . pray the sinner’s prayer. However, the definition of success, when measured by the “fruit that remains” (Jn.
Arn, Charles
core +2 more sources