A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
The Letter of Benedict XVI on Education: a guiding light for secularism and Catholicism
This work analyze the Letter of Pope Benedict XVI on „Educational Emergency’ (2008), that makes it essential for a new thinking on both the secular world and the catholic.
Elvira Lozupone
doaj
\firstpage 1 \pubyear2025 \keywordkeyword 1; keyword 2; keyword 3 (List three to ten pertinent keywords specific to the article; yet reasonably common within the subject discipline.) Macitentan adverse event profile: a pharmacovigilance study based on the FDA Adverse Event Reporting System (FAERS) from 2013 to 2024 [PDF]
Chenyue Gu +3 more
openalex +1 more source
How do scientific disciplines evolve in applied sciences? The properties\n of scientific fission and ambidextrous scientific drivers [PDF]
Mario Coccia
openalex +1 more source
An Overview of Learning Discipline in Secondary School Students
Sesila Harut, Sitti Anggraini
openalex +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Maternal Use of Physical Discipline and Children's Externalizing Problems Across Childhood in Singapore. [PDF]
Kyeong Y +9 more
europepmc +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source

