Results 41 to 50 of about 45,126 (263)

Discussions on the talent cultivation of cyber security

网络与信息安全学报, 2016
Cyber security has been formally approved to be the first level discipline in June 2015.How to train the cyber security talents that meet the needs of our country has become an urgent problem to be solved in the discipline construction.Synthetical ...
Jian WENG, Chang-she MA, Liang GU
doaj   +3 more sources

Exploring the impact of ICT interaction on students’ creative thinking across performance levels: an explainable AI perspective

Frontiers in Psychology
This study uses the PISA 2022 ICT questionnaire to examine how students’ ICT interaction behaviours in digital environments predict creative thinking across low, medium, and high performance levels (Class 0–2).
Xinhai Cai, Xinhai Cai, Yi Bi, Yonggang Feng   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Study on Business English Discipline Construction

Proceedings of the 2013 International Conference on Educational Research and Sports Education, 2013
This paper first investigates the theoretical foundation of business English discipline construction in our country and then discusses the necessity of business English discipline construction. Then, the paper presents a few issues to be noted in the process of business English discipline construction.
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Guided by National Strategic Needs， Striving to Build a First-Class Forensic Medicine Discipline — The Construction Plan for Forensic Medicine at Southern Medical University

Fayixue Zazhi
The 2024 National Education Work Conference pointed out that at the current juncture of the critical period for achieving the goals and tasks of the 14th Five-Year Plan, the implementation of the Education Powerhouse Construction Plan Outline should be ...
QIAO Dong-fang, QIU Ping-ming, WANG Qi, TAI Yun-chun, LI Dong-ri, XU Jing-tao, LUO Qi-zhi, HUANG En-ping, ZHU Bo-feng   +8 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Construction and High-Quality Development of Forensic Medicine Discipline at Sichuan University

Fayixue Zazhi
West China Forensic Medicine at Sichuan University （hereinafter referred to as West China Forensic Medicine） has a long history and profound cultural heritage.
LIANG Wei-bo
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source