Results 51 to 60 of about 7,451,038 (316)

Multi-outcome construction policies : comparative analysis of western australian and queensland policies [PDF]

open access: yes, 2009
This document provides an overview of the differences and similarities in the objectives and implementation frameworks of the training and employment policies applying to public construction projects in Western Australia and Queensland.

core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Typhoon short-term heavy precipitation warning based on dual-polarization radar observations of precipitation particle vertical distribution

open access: yesScientific Reports
Mesoscale convective systems within typhoon spiral rainbands often lead to localized short-term heavy precipitation, and their accurate prediction remains a challenging issue in operational meteorology.
Rong Fang, Ting Wang, Haoya Liu
doaj   +1 more source

Safer construction [PDF]

open access: yes, 2006
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core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The theoretical research on the discipline construction of pedagogy [PDF]

open access: yesProceedings of the 2015 3rd International Conference on Education, Management, Arts, Economics and Social Science, 2016
Education policy research on the problem of contemporary education, history and the social view of macroscopic idea for people to understand the contemporary education problem provides another perspective or way of thinking. This article through the review and summarize the pedagogy direction of the development and theory research, which is a good ...
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Clinically actionable classification tool for childhood and adult atopic dermatitis via explainable AI: a retrospective cross-sectional study optimizing diagnostic accuracy

open access: yesBioData Mining
Background Despite the critical role of early identification in managing atopic dermatitis (AD), current studies are limited by the absence of adult-specific risk stratification models and imbalanced cohort data, hindering effective risk profiling ...
Rong Zhou   +6 more
doaj   +1 more source

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