Results 51 to 60 of about 45,126 (263)
Frontiers in PsychologyIntroductionAlthough WeChat is widely adopted in Chinese higher-education English-translation programmes, little is known about how students actually use its group-chat function for collaborative learning or what problems arise.
Yuanxing Tan, Ran Ren
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Making Sense of Theory Construction: Metaphor and Disciplined Imagination [PDF]
Organization Studies, 2006 This article draws upon Karl Weick’s insights into the nature of theorizing, and extends and refines his conception of theory construction as ‘disciplined imagination’. An essential ingredient in Weick’s ‘disciplined imagination’involves his assertion that thought trials and theoretical representations typically involve a transfer from one epistemic ...
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
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Zhongguo cuzhong zazhi, 2019 首都医科大学附属北京天坛医院从建立神经内科，搭建神经病学学科建设平台的过程中， 以脑血管病为中心，全面发展神经病学各个亚专业，创建了包括多个神经科学相关临床专业、临床和 基础研究、统计学在内的神经病学中心。本文介绍了天坛医院瞄准国际前沿脉动，创新发展各个学科， 注重青年人才培养，在基础和临床研究领域做出了国际一流的突出成绩，改写国际指南，使得神经病 学科全面发展，其卓有成效的发展模式为全国神经病学中心建设和人才培养提供了典范和经验。 Abstract: This paper introduced
朱丽丽，赵性泉，王春雪，杜万良，王拥军
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
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Retracted: Reflections on the Discipline Construction Environment of World Literature and Comparative Literature in the Era of Big Data Analysis. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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Retracted: Discipline Construction and Development of Medical Universities in Complex Environment under Digital Technology and Structural Equation Model. [PDF]
J Healthc Eng, 2023 Engineering JOH.
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