Results 71 to 80 of about 7,425 (229)

Rapid clearance of cutaneous lesions with anifrolumab in SLE (systemic lupus erythematosus) and DLE (discoid lupus erythematosus)

JEADV Clinical Practice, Volume 4, Issue 1, Page 207-215, March 2025.
We treated 6 patients, suffering from SLE or DLE resistant to conventional treatments, with anifrolumab (monoclonal antibody that targets the type 1 interferon receptor subunit 1). The mean CLASI decreased by almost 60% at 1 to 2 months. The mean CLASI score at baseline was 14.2 ± 10.6 (median: 10.5) and decreased to 5.7 ± 5.3 (median: 3.0) after one ...
E. Parriel, C. Bulai‐Livideanu, M. Severino‐Freire, A. Delpuech, S. Faguer, J. Belliere, A. Huart, C. Paul   +7 more
wiley   +1 more source

Rowell's syndrome in an Indian male and review of the literature

Indian Dermatology Online Journal, 2015
Lupus erythematosus (LE) with erythema multiforme-like lesions with its characteristic serological picture had been described in 1963. We report a 33-year-old married male who presented with skin lesions of various morphology on different body parts ...
Bhushan Madke, Uday Khopkar
doaj   +1 more source

Hair regrowth in alopecia areata and re‐pigmentation in vitiligo in response to treatment: Commonalities and differences

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 3, Page 498-511, March 2025.
Hair Regrowth in Alopecia Areata. This scheme summarizes recent findings in hair follicle stem cell biology and their implication to regrow hair in alopecia areata. Hair follicle stem cells reside in hair bulge abundantly. Anagen drivers are enhanced and suppressed expression levels of activators and repressors at telogen, respectively.
Hiroki L. Yamaguchi, Yuji Yamaguchi, Elena Peeva   +2 more
wiley   +1 more source

COMO: A Pipeline for Multi-Omics Data Integration in Metabolic Modeling and Drug Discovery [PDF]

arXiv, 2020
Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly pipeline that integrates multi-omics data processing, context-specific metabolic model development, simulations, drug ...
arxiv  

Classifying discoid lupus erythematosus: background, gaps, and difficulties

International Journal of Women's Dermatology, 2017
To inform our ongoing efforts to develop defining features to be incorporated into a novel set of classification criteria for discoid lupus erythematosus (DLE), we conducted a literature review using the Ovid MEDLINE database.
Jessica S. Haber, BA, Joseph F. Merola, MD, MMSc, Victoria P. Werth, MD   +2 more
doaj  

Deformation of a biconcave-discoid capsule in extensional flow and electric field [PDF]

, 2018
Biconcave-discoid (empirical shape of a red blood cell) capsule finds numerous applications in the field of bio-fluid dynamics and rheology, apart from understanding the behavior of red blood cells (RBC) in blood flow. A detailed analysis is, therefore, carried out to understand the effects of the uniaxial extensional flow and electric field on the ...
arxiv   +1 more source

Text phrase‐mining in identifying and classifying maternal proteins and genes across preeclampsia and similar pathologies

Physiological Reports, Volume 13, Issue 6, March 2025.
Heat Map of Disease‐Protein and Disease‐Gene Associations. Context‐aware semantic online analytical processing (CaseOLAP) scores are represented across the Maternal Proteins and Genes (MPGs) on the x‐axis and the six Diseases of Interest (DOIs) on the y‐axis. Higher scores are depicted by darker cells.
Jacqueline G. Urdang, Stephanie Masters, Nneoma Edokobi, Chitra Mukherjee, Arnib Quazi, David A. Liem, Monica Ahrens, Xuan Wang, Megan Whitham   +8 more
wiley   +1 more source

Lupus erythematosus panniculitis in pregnancy

Indian Journal of Dermatology, 2015
A case of lupus erythematosus (LE) panniculitis in pregnancy without any lesions of discoid LE or systemic LE is being reported. There were no systemic symptoms.
Swati Gondane, Rajkumar Kothiwala, Sapna Dangi, Ashok Meherda   +3 more
doaj   +1 more source

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Arthritis &Rheumatology, Volume 77, Issue 2, Page 212-225, February 2025.
Objective Systemic inflammatory autoimmune diseases (SIADs) such as systemic lupus erythematosus (SLE), primary Sjögren disease (pSS), and idiopathic inflammatory myopathies (myositis) are complex conditions characterized by shared circulating autoantibodies and clinical manifestations, including skin rashes, among others.
Matteo Bianchi, Sergey V. Kozyrev, Antonella Notarnicola, Johanna K. Sandling, Mats Pettersson, Dag Leonard, Christopher Sjöwall, Iva Gunnarsson, Solbritt Rantapää‐Dahlqvist, Anders A. Bengtsson, Andreas Jönsen, Elisabet Svenungsson, Helena Enocsson, Marika Kvarnström, Helena Forsblad‐d'Elia, Sara Magnusson Bucher, Katrine B. Norheim, Eva Baecklund, Roland Jonsson, Daniel Hammenfors, Per Eriksson, Thomas Mandl, Roald Omdal, Leonid Padyukov, Helena Andersson, Øyvind Molberg, Louise Pyndt Diederichsen, Ann‐Christine Syvänen, Marie Wahren‐Herlenius, Gunnel Nordmark, Ingrid E. Lundberg, Lars Rönnblom, Kerstin Lindblad‐Toh, with the DISSECT consortium and the ImmunoArray consortium, Lars Rönnblom, Kerstin Lindblad‐Toh, Marie Wahren‐Herlenius, Gunnel Nordmark, Ingrid E. Lundberg, Ann‐Christine Syvänen, Johanna K. Sandling, Mateo Bianchi, Pascal Pucholt, Sergey V. Kozyrev, Maija‐Leena Eloranta, Dag Leonard, Andreas Jönsen, Anders A. Bengtsson, Iva Gunnarsson, Elisabet Svenungsson, Leonid Padyukov, Solbritt Rantapää‐Dahlqvist, Christopher Sjöwall, Helena Enocsson, Roland Jonsson, Roald Omdal, Daniel Hammenfors, Elke Theander, Eva Baecklund, Gudny Ella Thorlacius, Helena Forsblad‐d'Elia, Johan G. Brun, Juliana Imgenberg‐Kreuz, Karl A. Brokstad, Kathrine Skarstein, Katrine Brække Norheim, Lilian Vasaitis, Malin V. Jonsson, Marika Kvarnström, Per Eriksson, Sara Magnusson Bucher, Silke Appel, Svein Joar Johnsen, Thomas Mandl, Lara Adnan Aqrawi, Janicke Liaaen Jensen, Øyvind Palm, Albin Björk, Marie Fischer, Antonella Notarnicola, Anna Tjärnlund, Maryam Dastmalchi, Louise Pyndt Diederichsen, Maria Lidén, Øyvind Molberg, Thomas Skogh, Awat Jalal, Balsam Hanna, Helena Hellström, Tomas Husmark, Åsa Häggström, Anna Svärd, Jennifer Meadows, Jessika Nordin, Fabiana H. G. Farias, Johanna Dahlqvist, Argyri Mathioudaki, Daniel Eriksson, Kerstin Lindblad‐Toh, Gerli Rosengren Pielberg, Anna Lobell, Åsa Karlsson, Eva Murén, Göran Andersson, Kerstin M. Ahlgren, Lars Rönnblom, Maija‐Leena Eloranta, Nils Landegren, Olle Kämpe, Peter Söderkvist   +109 more
wiley   +1 more source

Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]

arXiv, 2018
Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv