Results 71 to 80 of about 127,925 (265)
Systemic Lupus Erythematosus with and without Anti-dsDNA Antibodies: Analysis from a Large Monocentric Cohort [PDF]
, 2015 Objectives. The anti-dsDNA antibodies are a marker for Systemic Lupus Erythematosus (SLE) and 70–98% of patients test positive. We evaluated the demographic, clinical, laboratory, and therapeutical features of a monocentric SLE cohort according to the ...
Alessandri, Cristiano +9 more
core +1 more source
Review of treatment for discoid lupus erythematosus
Dermatologic Therapy, 2016 Discoid lupus erythematosus (DLE) is a chronic cutaneous disease characterized by inflammatory plaques that, in the absence of prompt diagnosis and treatment, may lead to disfiguring scarring and skin atrophy. However, there is limited evidence for which
A. C. Garza-Mayers +2 more
semanticscholar +1 more source
Mechanism-based strategies for the management of autoimmunity and immune dysregulation in primary immunodeficiencies [PDF]
, 2016 A broad spectrum of autoimmunity is now well described in patients with primary immunodeficiencies (PIDs). Management of autoimmune disease in the background of PID is particularly challenging given the seemingly discordant goals of immune support and ...
Cooper, Megan A +4 more
core +2 more sources
Efalizumab in the Treatment of Discoid Lupus Erythematosus [PDF]
Archives of Dermatology, 2007 Discoid lupus erythematosus is a chronic inflammatory condition in which the pathogenesis and the role of cell-mediated immunity remains unclear. Currently, the most effective treatments for severe disease are thalidomide, methotrexate, and cyclosporin, although the evidence for this is limited.
Naila Usmani, Mark Goodfield
openaire +2 more sources
A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus
Medicine, 2018 Rationale: Lupus erythematosus tumidus (LET) is an uncommon type of cutaneous lupus erythematosus (CLE) that is rarely associated with other forms of lupus erythematosus.
Xiaomei Chen, Shenghong Wang, Li Li
semanticscholar +1 more source
Single-cell sequencing shows cellular heterogeneity of cutaneous lesions in lupus erythematosus
Nature Communications, 2022 Discoid lupus erythematosus (DLE) and systemic LE (SLE) can present as cutaneous lesions. Here the authors characterise an scRNA dataset of cutaneous lesions from these patients and compare these to healthy controls showing differential immune cell ...
Meiling Zheng +16 more
doaj +1 more source
Low Dose Thalidomide for Treatment of Resistant Discoid Lupus Erythematosus. A Case Report [PDF]
, 2013 Discoid lupus erythematosus (DLE) is a chronic, indolent, disfiguring disease that is characterized by scaly, erythematous, disk-shaped patches and plaques followed by atrophy, scarring and depigmentation.
Campos, S, Lestre, S, Ponte, P
core
Rapamycin for refractory discoid lupus erythematosus
Dermatologic Therapy, 2018 Generalized discoid lupus erythematosus can pose a therapeutic challenge for dermatologists. Current treatment emphasizes photoprotection, topical and systemic steroids, and steroid‐sparing immunosuppressive agents if necessary.
Mitchell Herold +4 more
semanticscholar +1 more source
Dermoscopy in general dermatology: A practical overview [PDF]
, 2016 Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders.
Errichetti, Enzo, Stinco, Giuseppe
core +1 more source
Oman Medical Journal, 2020 Objectives: We sought to determine the prevalence of immune-mediated skin disorders (IMDs), their oral manifestations, and the related comorbidity among Omani patients with IMDs attending the outpatient Department of Dermatology and Dental Clinic at Al ...
Abla Al Ismaili +3 more
doaj +1 more source