Results 1 to 10 of about 459,789 (287)

Predictors for short-term successful weaning from continuous renal replacement therapy: a systematic review and meta-analysis

Renal Failure, 2023
The systemic review and meta-analysis aimed to identify the predictors for short-term successful weaning from CRRT in severe AKI patients. PubMed, Embase, the Cochrane Library, and grey literature were searched for relevant studies investigating ...
Yu Li, Xiaoqi Deng, Jiaxing Feng, Bo Xu, Yulei Chen, Zhanying Li, Xiaodan Guo, Tianjun Guan   +7 more
doaj   +1 more source

Persistence with daily growth hormone among children and adolescents with growth hormone deficiency in the UK

Frontiers in Endocrinology, 2022
BackgroundChildren with growth hormone deficiency (GHD) are treated with daily somatropin injections; however, poor treatment persistence and adherence have been recognized previously and have been shown to negatively impact growth outcomes.
Jane Loftus, Jen Wogen, David Oliveri, Darrin Benjumea, Priti Jhingran, Yong Chen, Jose Alvir, Elena Rivero-Sanz, Jack C. Kowalik, Michael P. Wajnrajch, Michael P. Wajnrajch   +10 more
doaj   +1 more source

Discontinuous transcription [PDF]

Nucleus, 2018
Numerous studies based on new single-cell and single-gene techniques show that individual genes can be transcribed in short bursts or pulses accompanied by changes in pulsing frequencies. Since so many examples of such discontinuous or fluctuating transcription have been found from prokaryotes to mammals, it now seems to be a common mode of gene ...
Smirnov, Evgeny, Hornáček, Matúš, Vacík, Tomáš, Cmarko, Dušan, Raška, Ivan   +4 more
openaire   +2 more sources

Discontinuous neural networks and discontinuity learning

Journal of Computational and Applied Mathematics, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Della Santa, Francesco, Pieraccini, Sandra   +1 more
openaire   +1 more source

Tapered discontinuation vs. maintenance therapy of antipsychotic medication in patients with first-episode schizophrenia: Obstacles, findings, and lessons learned in the terminated randomized clinical trial TAILOR

Frontiers in Psychiatry, 2022
AimEvidence is insufficient regarding the consequences of discontinuing vs. maintaining antipsychotic medication in patients with first-episode schizophrenia. Our aim was to examine tapered discontinuation vs. maintenance treatment regarding remission of
Anne Emilie Stürup, Carsten Hjorthøj, Carsten Hjorthøj, Nikolai Albert, Nikolai Albert, Signe Dolmer, Merete Birk, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Lene Falgaard Eplov, Heidi Jensen, Ditte Lammers Vernal, Helene Speyer, Ole Mors, Merete Nordentoft   +14 more
doaj   +1 more source

Reversibility of Antipsychotic-Induced Weight Gain: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2021
Background and AimsWeight gain is a major adverse effect of antipsychotic medication, negatively affecting physical and mental well-being. The objective of this study was to explore if dose reduction, discontinuation, switch to a partial agonist, or ...
Helene Speyer, Casper Westergaard, Nikolai Albert, Mette Karlsen, Anne Emilie Stürup, Merete Nordentoft, Jesper Krogh   +6 more
doaj   +1 more source

Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands [PDF]

, 2020
Purpose: In June 2013 a European Medicines Agency referral procedure concluded that diclofenac was associated with an elevated risk of acute cardiovascular events and contraindications, warnings, and changes to the product information were implemented ...
Bennie, Marion, Doney, Alexander S. F., Ernst, Martin Thomsen, Flynn, Robert W. V., Hallas, Jesper, Herings, Ron M. C., MacDonald, Thomas M., Mackenzie, Isla S., Mitchell, Lyn, Morales, Daniel R., Morant, Steve V., Morris, Carole, Nicholson, Lizzie, Overbeek, Jetty A., Pottegard, Anton, Robertson, Chris, Smits, Elisabeth, Wei, Li   +17 more
core   +4 more sources

Results of interferon-based treatments in Alaska Native and American Indian population with chronic hepatitis C [PDF]

International Journal of Circumpolar Health, 2016
Background: There have been few reports of hepatitis C virus (HCV) treatment results with interferon-based regimens in indigenous populations. Objective: To determine interferon-based treatment outcome among Alaska Native and American Indian (AN/AI ...
Stephen E. Livingston, Lisa J. Townshend-Bulson, Dana J. T. Bruden, Chriss E. Homan, James E. Gove, Julia N. Plotnik, Brenna C. Simons, Philip R. Spradling, Brian J. McMahon   +8 more
doaj   +1 more source

Real-world treatment patterns, discontinuation and clinical outcomes in patients with B-cell lymphoproliferative diseases treated with BTK inhibitors in China

Frontiers in Immunology, 2023
IntroductionBruton tyrosine kinase inhibitor (BTKi) has demonstrated substantial efficacy in treating B-cell lymphoproliferative diseases (BLPD). Nonetheless, the significant discontinuation rates due to toxicity or financial reasons cannot be overlooked.
Yuting Yan, Yuting Yan, Rui Lv, Rui Lv, Tingyu Wang, Tingyu Wang, Ying Yu, Ying Yu, Yanshan Huang, Yanshan Huang, Wenjie Xiong, Wenjie Xiong, Yuxi Li, Yuxi Li, Weiwei Sui, Weiwei Sui, Qi Wang, Qi Wang, Wenyang Huang, Wenyang Huang, Gang An, Gang An, Dehui Zou, Dehui Zou, Jianxiang Wang, Jianxiang Wang, Lugui Qiu, Lugui Qiu, Shuhua Yi, Shuhua Yi   +29 more
doaj   +1 more source

Prevalence of and factors associated with contraceptive discontinuation in Kenya

African Journal of Primary Health Care & Family Medicine, 2022
Background: The overwhelming uptake of contraception in Kenya at 58% suggests huge potential for a continued increase, but discontinuation threatens efforts to achieve new targets.
Wambui Kungu, Alfred Agwanda, Anne Khasakhala   +2 more
doaj   +1 more source