Results 21 to 30 of about 459,789 (287)

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort [PDF]

open access: yes, 2019
Introduction: Concerns about dolutegravir (DTG) tolerability in the real-life setting have recently arisen. We aimed to estimate the risk of treatment discontinuation and virological failure of DTG-based regimens from a large cohort of HIV-infected ...
Abeli C.   +155 more
core   +4 more sources

THE DISCONTINUITY PROBLEM

open access: yesThe Journal of Symbolic Logic, 2022
AbstractMatthias Schröder has asked the question whether there is a weakest discontinuous problem in the topological version of the Weihrauch lattice. Such a problem can be considered as the weakest unsolvable problem. We introduce the discontinuity problem, and we show that it is reducible exactly to the effectively discontinuous problems, defined in ...
openaire   +2 more sources

Healthcare Utilization and Statin Re‐Initiation Among Medicare Beneficiaries With a History of Myocardial Infarction

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundContact with the healthcare system represents an opportunity for individuals who discontinue statins to re‐initiate treatment. To help identify opportunities for healthcare providers to emphasize the risk‐lowering benefits accrued through ...
John N. Booth   +11 more
doaj   +1 more source

A systematic review of the safety of tirzepatide-a new dual GLP1 and GIP agonist - is its safety profile acceptable?

open access: yesFrontiers in Endocrinology, 2023
AimsTirzepatide is a novel dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA). At present, there is no controversy over its effectiveness, but its safety. We conducted a systematic review to assess
Zhuqing Meng   +5 more
doaj   +1 more source

Health services research in the public healthcare system in Hong Kong: An analysis of over 1 million antihypertensive prescriptions between 2004-2007 as an example of the potential and pitfalls of using routinely collected electronic patient data [PDF]

open access: yes, 2008
<b>Objectives</b> Increasing use is being made of routinely collected electronic patient data in health services research. The aim of the present study was to evaluate the potential usefulness of a comprehensive database used routinely in the
A McCormack   +47 more
core   +4 more sources

Factors affecting continuation of clean intermittent catheterisation in people with multiple sclerosis: results of the COSMOS mixed-methods study [PDF]

open access: yes, 2018
Background:  Clean intermittent catheterisation (CIC) is often recommended for people with multiple sclerosis (MS).  Objective:  To determine the variables that affect continuation or discontinuation of the use of CIC.
Andrew Elders   +13 more
core   +5 more sources

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

open access: yes, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N   +6 more
core   +3 more sources

Hepatitis B Core-Related Antigen is a Biomarker for off-Treatment Relapse After Long-Term Nucleos(t)ide Analog Therapy in Patients with Chronic Hepatitis B

open access: yesInternational Journal of General Medicine, 2021
Guichan Liao,1,2 Xia Ding,1,2 Muye Xia,1,2 Yin Wu,1– 3 Hongjie Chen,1,2 Rong Fan,1,2 Xiaoyong Zhang,1,2 Shaohang Cai,1,2 Jie Peng1,2 1Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;
Liao G   +8 more
doaj  

Safety, adherence and discontinuation in varenicline solution nasal spray clinical trials for dry eye disease

open access: yesJournal of Comparative Effectiveness Research, 2023
Aim: Herein, we report safety outcomes for varenicline solution nasal spray (VNS) within the context of clinical trial discontinuation, contrasting those with discontinuation outcomes from topical cyclosporine and lifitegrast clinical trials. Materials
Alan G Kabat   +4 more
doaj   +1 more source

Lithium Prescribing during Pregnancy: A UK Primary Care Database Study [PDF]

open access: yes, 2015
Women taking lithium must decide whether to continue the medication if they conceive or plan to conceive.
Cowen, PJ   +6 more
core   +2 more sources

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