Results 61 to 70 of about 459,789 (287)
A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.Seda Susgun, Ozgu Kizek, Sibel Aylin Ugur Iseri, Ibrahim Kamaci, Ayse Deniz Elmali, Pinar Iscen, Berfin Gulkaya Guzel, Gul Yalcin Cakmakli, Bulent Elibol, Berril Donmez, Raif Cakmur, Pinar Topaloglu, Turkish NBIA Study Group, Abdullah Acar, Ahmet Acarer, Arzu Karabay, Asuman Ali, Ayla Barlas, Aysegul Gunduz, Banu Ozen Barut, Baris Baslo, Bilge Kocer, Bilgehan Mus, Birsen Karaman, Burcu Gokce Cokal, Cem Ismail Kucukali, Cenk Akbostanci, Ceyhun Sayman, Cagla Turan, Dilek Ince Gunal, Ebru Bilge Dirik, Ebru Erzurumluoglu, Elif Kocasoy Orhan, Enes Demiryurek, Emrah Yucesan, Ercan Kose, Erdem Tuzun, Esen Saka Topcuoglu, Esra Okuyucu, Fatma Betul Ozdilek, Feriha Ozer, Gencer Genc, Gozde Unal, Gulay Kenangil, Gullu Tarhan, Gunes Kiziltan, Halil Onder, Hamit Genc, Hasmet Hanagasi, Hatice Yuksel, Hulya Apaydin, Koray Kirimtay, Mehmet Guney Senol, Melisa Kilic, Meltem Demirkiran, Mert Karaca, Miray Erdem, Muhammet Bilgehan Mus, Murat Gultekin, Nalan Capan, Nazan Karagoz Sakalli, Nazli Basak, Nihan Hande Akcakaya, Ozan Ezer, Ozge Uygun, Ozge Yilmaz Kuspeci, Ozgur Oztop Cakmak, Pervin Iseri, Petek Ballar Kirmizibayrak, Pinar Elkoca, Recep Alp, Remzi Yigiter, Rezzak Yilmaz, Sadika Ozdemir, Selda Keskin, Selen Ilhan Alp, Selen Soylu, Serdar Ceylaner, Serhat Ozkan, Sevda Erer Ozbek, Sevgin Gundogan, Sevil Yasufli, Sezin Alpaydin Baslo, Sibel Ertan, Sultan Cagirici, Seyma Aykac, Vuslat Yilmaz, Yaprak Secil, Yasar Kutukcu, Yeliz Ciftci, Yesim Sucullu Karadag, Yildiz Değirmenci, Zeliha Matur, Nerses Bebek, Murat Emre, Zuhal Yapici +95 morewiley +1 more sourceReasons and Determinants of BoNT-A Treatment Discontinuation in Patients Living with Spasticity: A 10-Year Retrospective Analysis
Toxins, 2022 Background: The present study aimed to evaluate the reasons and determinants of BoNT-A discontinuation in patients with stroke, multiple sclerosis, spinal cord injury, and traumatic brain injury.Nicoletta Cinone, Luigi Santoro, Stefania Spina, Salvatore Facciorusso, Marco Battaglia, Alessio Baricich, Pasqua Marcogiuseppe, Andrea Santamato +7 moredoaj +1 more sourceDISCONTINUITY OF KNOWLEGDE
Beykent Üniversitesi Sosyal Bilimler Dergisi, 2017 M. Foucault and T. Kuhn concerned with the discontinuity of discourse in the sciences and social disciplines. In 1960s Kuhn stated that the natural science reflects basically a sequence of paradigm changes. In 1970s Foucault claimed a form of discourse about the growth of scientific knowledge in a range of human and medical sciences.openaire +3 more sourcesThe MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives
To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman +6 morewiley +1 more sourceComparing nuclear power trajectories in Germany and the UK: from ‘regimes' to ‘democracies’ in sociotechnical transitions
and Discontinuities [PDF]
, 2015 This paper focuses on arguably the single most striking contrast in contemporary major energy politics in Europe (and even the developed world as a whole): the starkly differing civil nuclear policies of Germany and the UK. Germany is seeking entirely to A Aliseda, A Bergek, A Blowers, A Corner, A Glaser, A Gramsci, A Held, A Hommels, A Lijphart, A Lijphart, A Lovins, A Massey, A Pegels, A Piening, A Schutz, A Sen, A Sen, A Smith, A Smith, A Smith, A Smith, A Smith, A Smith, A Stirling, A Stirling, A Stirling, A Verbruggen, Andy Stirling, B B F Wittneben, B Doherty, B Flyvbjerg, B Griffin, B Hancke, B K Sovacool, B K Sovacool, B K Sovacool, B K Sovacool, B Latour, B Turnheim, B Wynne, B Wynne, Bbc News, Blowers, Bvg Associates, C A Miller, C Barnett, C C R Penna, C Cottarelli, C Crouch, C Klessmann, C Kuzemko, C Li, C M Hendriks, C M Hendriks, C Mitchell, D Campbell, D Clements, D Elliott, D Haraway, D Harvey, D J Hess, D J Hess, D Jahn, D Jahn, D Johnson, D King, D P Mccormack, D Rucht, D Toke, D Toke, Decc, Decc, Decc, E F Borgatta, E Kahn, E Laclau, E Laclau, E Shove, E Shove, E Swyngedouw, Edf Energy, Enf Solar, Ewea, F Berkhout, F Berkhout, F Geels, F Geels, F Kern, F Kern, F Kern, F Kern, F Kern, F L�v�que, F Malerba, F W Geels, F W Geels, F W Geels, F W Geels, F W Geels, F W Geels, Ffree, G C Unruh, G Harris, G Hecht, G L Munck, G Mackerron, G Munk, G Resch, G Resch, G Ritzer, G Smith, G Strohmeier, G Verbong, G Verbong, G Winter, German Bundestag, Globalscan, Gns, H Chalmers, H E Normann, H Marcuse, H P Kitschelt, Hm Government, Hm Government, I Bailey, I Lovinfosse, I Welsh, Iaea, Ipsos Mori, Irena, J A Camilleri, J Allouche, J Byrne, J C Scott, J Deign, J Dewey, J Downing, J Grin, J Huenteler, J Jewell, J Lipp, J Markard, J Markard, J Meadowcroft, J Mecklin, J Nill, J Pligt, J R Josephson, J Rotmans, J S Dryzek, J Schot, J Wilson, K Barnham, K Bergeron, K Bickerstaff, K Bruninx, K Hartley, K Kleiner, K Pavitt, K Rogge, K Smith Stegen, L Arnold, L Baker, L Coenen, L Magnani, L Veneklasen, L Winner, L�v�que, M Berth�lemy, M Blyth, M Bookchin, M B�hlmann, M B�hlmann, M J Witkamp, M Leach, M Lenzen, M Lockwood, M Lockwood, M Lockwood, M Lynas, M M Smink, M Mazzucato, M Purdue, M R Fhg-Isi, M Schneider, M V Ramana, M Weber, Mod, N Carter, N E Hultman, N Guild, N Luhmann, N Marres, Nukem, O Renn, P Bourdieu, P Bradford, P Delrio, P Hall, P Hall, P Johnstone, P Linares, P Pierson, P Stegmaier, Philip Johnstone, R Cowan, R Cowell, R E H Sims, R Eckstein, R Edwards, R Kemp, R Kemp, R Milne, R Nelson, R Norris, R Raven, R Simon, R Yin, Renewableuk, Rip, Royce Rolls, S ?i?ek, S ?i?ek, S Ansari, S Jacobsson, S Jasanoff, S Jasanoff, S Jhagroe, S Lukes, S Squassoni, S Strunz, S Thomas, S Thomas, S Thomas, Schrader-Frechette, T Bijker, T Hughes, T O&apos, U J�rgensen, U K Germany, Urenco, V Lauber, V M Fthenakis, W Arthur, W L�tkenhorst, W Nuttall, W Patterson, W Patterson, W Rudig, W Walker, Y Peng, Y.-H Sun +251 morecore +1 more sourceInhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel +14 morewiley +1 more sourceDeep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik +7 morewiley +1 more sourceTherapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group [PDF]
, 2019 Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established.Badalamenti, G., Bianco, A., Colao, A., De Divitiis, C., Di Maio, S., Di Sarno, A., Dolce, P., Faggiano, A., Guarnotta, V., Leo, S., Mocerino, C., Modica, R., Ottaviano, M., Palmieri, G., Puliafito, I., Riccardi, F., Tafuto, S., Tozzi, L. +17 morecore +1 more source