Results 41 to 50 of about 24,168 (302)

Presupposition in discourse: theoretical and methodological issues [PDF]

open access: yes, 2014
This paper is concerned with the concept of ‘presupposition’, specifically as it is applied in critical approaches to discourse analysis such as Critical Discourse Analysis or Societal Pragmatics, and proposes a systematisation of a socio-cognitive ...
Polyzou, A.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

AUDIENCE AWARENESS IN THE WRITTEN DISCOURSE OF SUDANESE EFL UNIVERSITY LEARNERS

open access: yesEnglish Review: Journal of English Education, 2014
The study investigates the written discourse of the Sudanese EFL university learners to evaluate and assess their awareness of the audience to whom they write. The analytic descriptive approach is adopted to achieve the aims of the study. The subjects of
Ali Ahmed Osman Zakaria   +1 more
doaj  

A Critical Approach to L2 Classroom Discourse Competence

open access: yesPraxisForschungLehrer*innenBildung, 2023
This article develops a proposal for a Critical Second Language (L2) Classroom Discourse Competence (CDC) for (English) language teachers. The proposal takes the comprehensive competence model as a starting point which Thomson (2022) presents in her ...
Peter Schildhauer
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Communicative Competence in English Among Junior High School Students

open access: yesJPAIR
Developing communicative competence is one of the expected outcomes of the Language Arts and Multiliteracies Curriculum (LAMC). This study evaluates the communicative competence among Junior High School students at Vinapor National High School. Employing
Ann Jane Samaranos, Isidro Biol Jr.
doaj   +1 more source

LINGUISTIC EXPERTISE IN LEGAL DISCOURSE: TYPES AND ASPECTS

open access: yesВестник Кемеровского государственного университета, 2017
The article is devoted to the relevance of special linguistic knowledge in legal discourse and the determination of the competence of an expert linguist. It features the analyses of the basis for the use of linguistic expertise in the aspect of the legal
M. V. Batyushkina
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

The ‘Competence’ discourse in education and the struggle or social agency and critical citizenship [PDF]

open access: yes, 2009
This paper argues for an education for critical citizenship closely connected with a revitalisation of the democratic public sphere and which prepares citizens to contribute to the emergence of a ‘substantive democracy’ (Giroux, 2001). An education for
Mayo, Peter
core  

Male and Female Students’ Discourse Competence at Kalamansig National High School [PDF]

open access: yes, 2021
The study aimed to determine the relationship between the oral and written discourse competence of the male and female students of Kalamansig National High School. Specifically, it sought to determine the level of oral and written discourse competence of
Aliman, Bai Donna S.   +2 more
core   +2 more sources

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