Results 91 to 100 of about 167,584 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

“Bien mirado”: Absolute Clause and Discourse Marker

open access: yesCatalan Journal of Linguistics
This paper analyzes the construction bien mirado as a discursive marker. In the first part, based on the data provided by the CDH and CORPES corpora, we will examine the discursive functioning of bien mirado and the delimitation problems associated with
José Luis Cifuentes Honrubia
doaj   +1 more source

The Little Words That Matter: Discourse Markers in Teacher Talk [PDF]

open access: yes, 2015
Tujuan dari artikel ini adalah untuk membahas suatu aspek khusus dari interaksi kelas dan penggunaan bahasa di kelas bahasa yakni penanda wacana (DMs). Penelitian ini menggunakan metode studi kasus.
Karlina, Y. (Yeni)   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

CULTURAL RELATION ON DISCOURSE MARKERS IN PUNCHLINES ON RICKY GERVAIS’ SUPERNATURE STAND-UP COMEDY SHOW

open access: yesJournal Sampurasun
This research investigates the intricate functions of discourse markers (DMs) in Ricky Gervais' stand-up comedy, exploring their alignment with humour theories and their impact on punchline delivery.
Azzahra Amalia, Heri Heryono
doaj   +1 more source

Hedging in written academic discourse as manifestation of its dialogue nature (based on dissertation reviews) [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия Филология, Журналистика
The article presents the analysis of the dialogue nature of written academic communication based on Russian evaluative academic discourse. The texts of 70 official dissertation reviews in humanities and sciences, published on the sites of dissertation ...
Viktorova, Elena Yuryevna
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Étude du marqueur discursif ouais dans l’oral spontané : approche syntaxique et discursive

open access: yesCorela
This article examines the discursive functions of the discourse marker ouais when it appears in different syntactic positions in two excerpts from the MPF (Multicultural Paris French) spontaneous speech corpus.
Peng Yuanlong
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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