Results 81 to 90 of about 11,180 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

De l’adverbe de manière au marqueur discursif : le cas de autrement [PDF]

open access: yesStudii de Lingvistica, 2019
The present research focuses on the French adverb autrement, which is characterized by a wide range of uses. This allows it to function not only as an adverb of manner that modifies the verb, but also as a discourse marker that the speaker employs to ...
Céline Corteel
doaj  

Jæʕne dans le discours des Libanais : pragmaticalisation, distribution et emplois d’un marqueur discursif déverbal

open access: yesDiscours, 2013
This paper deals with jæʕne, a Lebanese discourse marker (also used by Syrian, Palestinian and Egyptian speakers). Jæʕne can be translated as it means, that is to say, I mean, you mean, or even by a filled pause.
Layal Kanaan
doaj   +1 more source

The French Discourse Marker Mais Dame: Past and Present Functions

open access: yes, 2008
We examine the evolution and current use of the French discourse marker mais dame, whose usage was first attested in Metropolitan French early in the 19th century.
Ruth King, Gary R. Butler
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Understanding discourse markers in interpreter-mediated police interviews [PDF]

open access: yes
Despite the growing prevalence of interpreter-mediated police interviews, this area remains widely under-researched as the focus of research on legal interpreting has been the discourse of the courtroom.
Gallai, F
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

SO, Discourse Marker: Invariance, Positioning and Prosody

open access: yesAnglophonia
Discourse markers (DM) are words or expressions that help to link utterances cohesively in larger chunks of discourse. In spontaneous oral English, the discourse marker SO can appear in a few positions between two utterances, and therefore also between ...
Steven Schaefer
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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