Results 71 to 80 of about 169,123 (346)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

“Bien mirado”: Absolute Clause and Discourse Marker

open access: yesCatalan Journal of Linguistics
This paper analyzes the construction bien mirado as a discursive marker. In the first part, based on the data provided by the CDH and CORPES corpora, we will examine the discursive functioning of bien mirado and the delimitation problems associated with
José Luis Cifuentes Honrubia
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Welche Sprache ist sie anyway?: Borrowed anyway/anyhow in Texas German [PDF]

open access: yes, 2018
A common phenomenon when languages are in contact is for one language to borrow words or phrases from another and incorporate them into the native vocabulary.
Jesswein, Victoria
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A emergência de domínio funcional e a abordagem construcional da gramática: o caso do que nem no Português Brasileiro

open access: yesRevista Odisséia, 2019
According to the language conception adopted by the Construction Grammar (CROFT, 2001) and the constructional perspective of change (TRAUGOTT; TROUSDALE, 2013; TEIXEIRA; ROSÁRIO, 2016), we aim, in this study, to analyze the functional domain of the “que ...
Caio Aguiar Vieira   +1 more
doaj   +1 more source

S bolshego u menya vsyo khorosho: one discourse marker in the Belarusian variety of Russian

open access: yesOpera slavica, 2018
The paper focuses on the semantics and usage of the discourse maker s bolshego (more frequent variant) and sbolshego (less frequent one) in Russian speech. The data for the research was gathered from linguistic corpora.
Ol'ga Gorickaja
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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