Results 121 to 130 of about 207,019 (347)

From ergativus absolutus to topic marking in Kiranti : a typological perspective [PDF]

, 2010
In many languages, clauses can be subordinated by means of case markers. For Bodic languages, a branch of Sino-Tibetan, Genetti (1986) has shown that the meaning of case markers on clauses is in most instances a natural extension of their function on ...
Bickel, Balthasar
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Discourse markers in Shajara-i Tarākima

Humanities & Social Sciences Communications
Shajara-i Tarākima, transcribed in Classical Chagatai Turkic by Abu al-Ghazi Bahadur Khan during the 17th century, is one of the most significant works in Turkology studies.
Hayrullah Kahya
doaj   +1 more source

Discourse Markers (DMs) in Classroom Oral Presentation of Arab Postgraduate Students

, 2022
Hussein W. Alkhawaja, Shamala Paramasivam, Vahid Nimehchisalem, Zalina Mohd Kasim   +3 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Usos marginales de los marcadores del discurso. Su efecto en la comprensión lectora en español como lengua extranjera

Ibérica, 2003
The aim of this paper is to investigate what we have called marginal uses of discourse markers and their effect on reading comprehension in Spanish as a foreign language.
Ana Cristina Lahuerta Martínez, María Fernanda Pelayo   +1 more
doaj  

Discourse Markers in Works of Russian Linguists: Functional-Pragmatic and Functional-Semantic Approaches

Научный диалог
This article addresses the issue of discourse markers as illuminated by the works of Russian scholars. The relevance of the study is justified by the necessity of theoretical understanding of existing scientific approaches to the examination of these ...
A. V. Kuleshova, T. V. Slastnikova
doaj   +1 more source

Exploring the Use of Discourse Markers in EFL Students’ Writing through Google Docs

, 2022
Atef Odeh AbuSa’aleek
openalex   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source