Results 51 to 60 of about 11,790 (293)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Discourse: Space for the constitution of the subject
Colombian Applied Linguistics Journal, 2012 Discourse has been pointed as a site of struggle for power. However, when analyzing the teachers’ discourse of resistance to educationalreforms has been privileged an orientation that prescribes discourse-power relations to mere relations of protest and ...
Pilar Méndez Rivera
doaj
Online Brazilian Journal of Nursing, 2010 The complexity of a cardiac surgery and the advancement of the technology involved, can hamper the nurse´s awareness, in the pre-operatory stage, of the different needs of the patient who will undergo this procedure. Thus, this study is an Academic Master´s dissertation project in the Science of Health Care from the Fluminense Federal University.
Thalita Gomes do Carmo +1 more
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Perceptions about the role of nurses in people at the end of life
Revista de Enfermagem da Universidade Federal de Santa Maria, 2021 Objective: describe the perception of nursing students about the role of nurses in people at the end of life. Method: qualitative, descriptive study, with data collected at a private university in Curitiba.
Ana Paula Hey +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Mediale Erinnerungsbilder im gegenwärtigen deutsch-polnischen Diskurs um Vertriebene
Stylistyka, 2020 The aim of the article is to answer the following research questions: (1) Which memory images can be reconstructed in the binational discourse about expulsions? (2) Which processes of linguistic realisation do they undergo?
Dorota Kaczmarek
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source