Results 51 to 60 of about 12,381 (255)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Repercussions of imprisonment for conjugal violence: discourses of men
Revista Latino-Americana de EnfermagemObjective: to know the consequences that men experience related to incarceration by conjugal violence. Methods: qualitative study on 20 men in jail and indicted in criminal processes related to conjugal violence in a Court specialized in Family and ...
Anderson Reis de Sousa +5 more
doaj +1 more source
Diacronie. Studi di Storia Contemporanea, 2022 Within the consumerist dimension of history, which has seen a remarkable development with the wide propagation of audio-visual materials in streaming platforms, each society produces self-representations that allow the strengthening of certain shared ...
Christopher CALEFATI
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Online Brazilian Journal of Nursing, 2010 The complexity of a cardiac surgery and the advancement of the technology involved, can hamper the nurse´s awareness, in the pre-operatory stage, of the different needs of the patient who will undergo this procedure. Thus, this study is an Academic Master´s dissertation project in the Science of Health Care from the Fluminense Federal University.
Thalita Gomes do Carmo +1 more
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
THE TRAINING OF COMPETENCES FOR MANAGEMENT IN NURSING
Cogitare Enfermagem, 2014 The objective of this exploratory-descriptive study was to identify the knowledge, skills and attitudes learned by 22 graduates from an undergraduate course in the issue of Management in Nursing.
Maria de Lourdes de Almeida +3 more
doaj +1 more source
Knowledge of nurses about the importance of the use of care protocols: Collective subject discourse
, 2021 Objetivo: investigar el conocimiento de los enfermeros de cuidados intensivos sobre la prevención y evaluación de riesgos relacionados con la LPP y la importancia del uso de protocolos de atención de enfermería. Métodos: Se trata de un estudio exploratorio-descriptivo con enfoque cualitativo.
Lima, Rayra Mass Lucena de Sena +9 more
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source