Results 131 to 140 of about 19,470,595 (297)

Discovery

open access: yes, 1929
Parties litigant desire to obtain before trial all possible information relevant to the matter in issue. Obviously their opponents possess much of this information but are usually reluctant to divulge it.
James, Fleming
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Financial hardship after COVID-19 infection among US Veterans: a national prospective cohort study

open access: yesBMC Health Services Research
Background Research suggests an association between COVID-19 infection and certain financial hardships in the shorter term and among single-state and privately insured samples.
Diana J. Govier   +15 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Comprehensive annual financial report for the year ended ... (Online); Comprehensive annual financial report

open access: yes, 2003
Annual; Dec. 31, 2002-; Description based on: 2002; title from PDF cover (viewed on Jan.
Ohio Public Employees Retirement System.
core  

Price discovery in spot and futures markets: a reconsideration [PDF]

open access: yes, 2009
We reconsider the issue of price discovery in spot and futures markets. We use a threshold error correction model to allow for arbitrage operations to have an impact on the return dynamics.
Theissen, Erik
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Navigating the future

open access: yes, 2003
Annual; Dec. 31, 2002-; Title varies slightly.; Vol. for 2003- are for the years ended Dec. 31, 2003 & 2002-; Prepared under the direction of the OPERS Finance Division.; Harvested from the web on 7/25 ...
Ohio Public Employees Retirement System.
core  

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