Results 111 to 120 of about 2,897 (246)
A Deterministic Learning Approach Based on Discrepancy
, 2003 The general problem of reconstructing an unknown function from a finite collection of samples is considered, in case the position of each input vector in the training set is not fixed beforehand, but is part of the learning process. In particular, the
Cristiano Cervellera, Marco Muselli
core +1 more source
Mulla Sadra on the External Difference between Accident and Subject of Philosophical Secondary Intelligible [PDF]
حکمت معاصر, 2014 The Mulla Sadra’s view on the existence of philosophical secondary intelligible has been interpreted and expressed diversely. What is easily understood from Sadra’s statements is that the external aspect of philosophical secondary intelligible is ...
Mohammad Hosseinzadeh
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Scientific ReportsAccording to the Cosmological Principle an observer stationary with respect to the comoving coordinates of the expanding universe should find the redshift distribution of distant quasars to be isotropic.
Ashok K. Singal
doaj +1 more source
On existence of a variational regularization parameter under Morozov's discrepancy principle
CoRRMorozov's discrepancy principle is commonly adopted in Tikhonov regularization for choosing the regularization parameter. Nevertheless, for a general non-linear inverse problem, the discrepancy $\|F(x_α^δ)-y^δ\|_Y$ does not depend continuously on $α$ and it is questionable whether there exists a regularization parameter $α$ such that $τ_1δ\leq \|F(x_α ...
Liang Ding +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
On the lower expected star discrepancy for jittered sampling than simple random sampling
, 2023 We compare expected star discrepancy under jittered sampling with simple random sampling, and the strong partition principle for the star discrepancy is proved.Comment: 12pages, 2 figures.
Xu, Xiaoda, Xian, Jun
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Smoothed discrepancy principle as an early stopping rule in RKHS
, 2019 International audienceIn this paper we work on the estimation of a regression function that belongs to a polynomial decay reproducing kernel Hilbert space (RKHS). We describe spectral filter framework for our estimator that allows us to deal with several
Averyanov, Yaroslav +2 more
core
Inexact Bregman iteration with an application to Poisson data reconstruction
, 2013 This work deals with the solution of image restoration problems by an iterative regularization method based on the Bregman iteration. Any iteration of this scheme requires to exactly compute the minimizer of a function.
Ruggiero, V +3 more
core +1 more source