Results 71 to 80 of about 1,273,558 (290)
On the discrepancy principle and generalised maximum likelihood for regularisation [PDF]
Bulletin of the Australian Mathematical Society, 1995 Let fnλ be the regularised solution of a general, linear operator equation, K f0 = g, from discrete, noisy data yi = g(xi ) + εi, i = 1, …, n, where εi are uncorrelated random errors with variance σ2. In this paper, we consider the two well–known methods – the discrepancy principle and generalised maximum likelihood (GML), for choosing the crucial ...
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Using the quantum probability ranking principle to rank interdependent documents [PDF]
, 2010 A known limitation of the Probability Ranking Principle (PRP) is that it does not cater for dependence between documents. Recently, the Quantum Probability Ranking Principle (QPRP) has been proposed, which implicitly captures dependencies between ...
Azzopardi, L. +5 more
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INFORMATION BASE OF ENSURING ECONOMIC SECURITY OF THE ENTERPRISE
Вестник Российского экономического университета имени Г. В. Плеханова, 2017 The article deals with specific features of the information base functioning, which is used to ensure economic security of the enterprise. The author pays attention to principle official sources, gives their brief characteristics and shows opportunities ...
Eugene O. Savchenko
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
On the Epistemology of the Precautionary Principle [PDF]
, 2014 In this paper we present two distinctly epistemological puzzles that arise forone who aspires to defend the precautionary principle. The first puzzle involves anapplication of contextualism in epistemology; and the second puzzle concerns the task of ...
Carter, J.A. +5 more
core +2 more sources
Proton-3He elastic scattering at low energies and the “Ay Puzzle”
EPJ Web of Conferences, 2010 The Kohn variational principle and the hyperspherical harmonic technique are applied to study p − 3He elastic scattering at low energies. Preliminary results obtained using several interaction models are reported.
Kievsky A. +4 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On the generalized discrepancy principle for Tikhonov regularization in Hilbert scales [PDF]
Journal of Integral Equations and Applications, 2010 For solving linear ill-posed operator equations \(A_0 x=y_0\), where \(A_0\) acts between Hilbert spaces \(X\) and \(Y\), the method of Tikhonov regularization in Hilbert scales \(\min_{x \in X} \{ \| A_h x-y_{\delta}\|^2+\alpha \| B^s x \|^2 \}\) \((\alpha>0, s\geq 0)\) is investigated. Here, \(B: D(B) \subset X \to X\) is an unbounded densely defined
Lu, S. +3 more
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