Results 61 to 70 of about 2,897 (246)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Morozov's Discrepancy Principle Under General Source Conditions [PDF]

open access: yes, 2002
In this paper we study linear ill-posed problems Ax = y in a Hilbert space setting where instead of exact data y noisy data y^delta are given satisfying |y - y^delta|
Schock, Eberhard   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regularization properties of the sequential discrepancy principle for Tikhonov regularization in Banach spaces [PDF]

open access: yes, 2013
The stable solution of ill-posed non-linear operator equations in Banach space requires regularization. One important approach is based on Tikhonov regularization, in which case a oneparameter family of regularized solutions is obtained. It is crucial to
Anzengruber, Stephan W.   +2 more
core  

A modified discrepancy principle to attain optimal convergence rates under unknown noise

open access: yes, 2021
We consider a linear ill-posed equation in the Hilbert space setting. Multiple independent unbiased measurements of the right-hand side are available.
Jahn, Tim Nikolas
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

INFORMATION BASE OF ENSURING ECONOMIC SECURITY OF THE ENTERPRISE

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2017
The article deals with specific features of the information base functioning, which is used to ensure economic security of the enterprise. The author pays attention to principle official sources, gives their brief characteristics and shows opportunities ...
Eugene O. Savchenko
doaj   +1 more source

Discrepancy principle for DSM

open access: yes, 2006
Let $Ay=f$, $A$ is a linear operator in a Hilbert space $H$, $y\perp N(A):=\{u:Au=0\}$, $R(A):=\{h:h=Au,u\in D(A)\}$ is not closed, $\|f_δ-f\|\leqδ$. Given $f_δ$, one wants to construct $u_δ$ such that $\lim_{δ\to 0}\|u_δ-y\|=0$. A version of the DSM (dynamical systems method) for finding $u_δ$ consists of solving the problem \bee \dotu_δ(t)=-u_δ(t)+T^{
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Proton-3He elastic scattering at low energies and the “Ay Puzzle”

open access: yesEPJ Web of Conferences, 2010
The Kohn variational principle and the hyperspherical harmonic technique are applied to study p − 3He elastic scattering at low energies. Preliminary results obtained using several interaction models are reported.
Kievsky A.   +4 more
doaj   +1 more source

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