Results 11 to 20 of about 4,542,490 (265)

Incorporating Discontinuous Preferences into the Analysis of Discrete Choice Experiments [PDF]

, 2007
Discontinuous preferences, Discrete choice experiments, Multinomial error component logit model, Rural environmental landscapes, Willingness to pay,
Scarpa, R., Scarpa, R, Scarpa, Riccardo, Campbell, Danny, Hutchinson, WG, Hutchinson, W George, Campbell, D., Hutchinson, W. George, W. Hutchinson, Danny Campbell, Campbell, D, Riccardo Scarpa, Hutchinson, W.G., Hutchinson, George; id_orcid   +13 more
core   +1 more source

A review of the application and contribution of discrete choice experiments to inform human resources policy interventions. [PDF]

, 2009
Although the factors influencing the shortage and maldistribution of health workers have been well-documented by cross-sectional surveys, there is less evidence on the relative determinants of health workers' job choices, or on the effects of policies ...
Lagarde, Mylene, Lagarde Mylene, Blaauw Duane, Duane Blaauw, Mylene Lagarde, Blaauw, Duane   +5 more
core   +2 more sources

Policy interventions that attract nurses to rural areas: a multicountry discrete choice experiment. [PDF]

, 2010
OBJECTIVE: To evaluate the relative effectiveness of different policies in attracting nurses to rural areas in Kenya, South Africa and Thailand using data from a discrete choice experiment (DCE). METHODS: A labelled DCE was designed to model the relative
Mudhune, S, Mullei, K, M English, M Lagarde, N Pagaiya, Blaauw, D, Tangcharoensathein, V, K Mullei, E Erasmus, Erasmus, E, Pagaiya, N, V Tangcharoensathein, Goodman, C, English, M, English, Mike, Lagarde, M, S Mudhune, D Blaauw, C Goodman   +18 more
core   +1 more source

A discrete choice experiment investigating preferences for funding drugs used to treat orphan diseases: an exploratory study [PDF]

, 2010
Policy debate about funding criteria for drugs used to treat rare, orphan diseases is gaining prominence. This study presents evidence from a discrete choice experiment using a convenience sample of university students to investigate individual ...
Jeremiah Hurley, Mentzakis, Emmanouil, Stefanowska, Patricia, Emmanouil Mentzakis, Patricia Stefanowska, Hurley, Jeremiah   +5 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Preferences of Hungarian consumers for quality, access and price attributes of health care services — result of a discrete choice experiment [PDF]

, 2012
In 2010, a household survey was carried out in Hungary among 1037 respondents to study consumer preferences and willingness to pay for health care services.
Groot, W., Pavlova, Milena, Groot, Wim, Baji, Petra, Baji, P., Gulácsi, László, Pavlova, M., Gulácsi, L., László Gulácsi, Milena Pavlova, Wim Groot, Petra Baji   +11 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source